Abstract Background and Objective: According to the importance of learning and memory in the human life and also unavoidable neural degeneration due to aging, finding new compounds (drugs) against this process is valuable. However, there are many recommendations for herbal medicine and constituents which encouraged us to examine a candidate plant Zingiber officinalis for the mentioned purpose. ...

introduction: olibanum improves memory in different models of learning. however, the effect of olibanum on models of alzheimer’s disease has been less studied. in the present study, the effect of olibanum on memory in normal rats and in a rat model of alzheimer disease induced by intracerebroventricular injections of streptozotocin was evaluated. methods: rats received an aqueous extract of oli...

Introduction: Nitric oxide is an important messenger in hippocampal region which is affected in learning and memory processes and hippocampal responses to stress. In this study, we investigated the effect of L-NAME on passive avoidance memory in adult male rats exposed to restraint-stress. Methods: For this purpose, male Wistar rats were bilaterally implanted with cannulas aimed at the CA1 r...

Introduction: Olibanum improves memory in different models of learning. However, the effect of olibanum on models of Alzheimer’s disease has been less studied. In the present study, the effect of olibanum on memory in normal rats and in a rat model of Alzheimer disease induced by intracerebroventricular injections of streptozotocin was evaluated. Methods: Rats received an aqueous extract of...

these experiments examined the effects of pre-test intra dorsal hippocampus (intra-ca1) administration of gabaa receptor agonist and antagonist, muscimol and bicuculline respectively, on state-dependent learning induced by lithium. male nmri mice were trained in a one-trial step-down inhibitory avoidance task, and immediately after training they received ip injections of either saline (10 ml/kg...

Introduction: Learning and memory processes result from interaction of neurotransmitter systems in various brain regions such as amygdala and hippocampus. Considering that morphine induces memory impairment, in the current study, we examined the possible role of cholinergic muscarinic receptor s of the central amygdala (CeA) on the morphine-induced amnesia in adult male Wistar rats. Methods: A ...