background: the fc receptor like (fcrl) molecules belong to the immunoglobulin (ig) superfamily with potentially immunoregulatoryfunction. among the fcrl family fcrl2 and 4 are predominantly expressed on memory b cells and fcrl1 is a pan- b cell marker. to date, noligand has been identifid for the human fcrl1, 2 and 4 molecules.objectives: cloning, expression, purifiation and structural analysi...

Objective(s): Erythropoietin (EPO), is a 34KDa glycoprotein hormone, which belongs to type 1 cytokine superfamily. EPO involves in erythrocyte maturation through inhibition of apoptosis in erythroid cells. Besides its main function, protective effects of EPO in heart and brain tissues have been reported. EPO has a critical role in development, growth, and homeostasis of brain. Furthermore EPO h...

aim : evaluation of biological characteristics of 13 identified proteins of patients with cirrhotic liver disease is the main aim of this research.   background : in clinical usage, liver biopsy remains the gold standard for diagnosis of hepatic fibrosis. evaluation and confirmation of liver fibrosis stages and severity of chronic diseases require a precise and noninvasive biomarkers. since the...

background: the human seminal fluid is a complex body fluid. it is not known how many proteins are expressed in the seminal plasma; however in analog with the blood it is possible up to 10,000 proteins are expressed in the seminal plasma. the human seminal fluid is a rich source of potential biomarkers for male infertility and reproduction disorder. methods: in this review, the ongoing list of ...

background: sparganosis is caused by the invasion of spirometra sparganum into various tissues/organs. subcutaneous sparganosis can be diagnosed by biopsy , while visceral/cerebral sparganosis is not easy to be diagnosed. the diagnosis de-pends largely on the detection of specific anti-sparganum antibodies. t he specific-ity of the elisa could be increased by using s. mansoni sparganum excretor...

background: taenia multiceps is a cestode parasite with its larval stage(metacestode), coenurus cerebralis , mainly encysts in the central nervous system of sheep and other livestock causing cerebralis coenurosis. since treatment of coenurosis with chemotherapy showed little effect and surgical removal of cysts is not advisable in field conditions, vaccination is useful to control coenurosis. p...

Abstract Establishing any characteristic associations between the serum parameters of thyroid function and proteins in pregnancy may aid elucidating role gland regulation pregnancy-specific metabolic processes selecting candidate biomarkers for use their clinical assessment. Concentrations stimulating hormone (TSH), free tri-iodothyronine (fT3) thyroxine (fT4), six electrophoretically separated...

background/objective: development of a new enzyme-linked immunosorbent assay (elisa) for screening human blood serum and plasma for antibodies to human immunodeficiency virus type 1 (hiv1) and type 2 (hiv2) as hiv1/2rec elisa diagnostic kit based on e. coli derived soluble recombinant proteins.   methods : polypeptides corresponding to hiv1 gp41 and hiv2 gp36 immunodominant regions and hiv1 gag...