Background and Objective: Cutaneous cytology is the study of scraping or smears obtained from skin lesions. Although not commonly employed, cutaneous cytology has been a useful tool for clinicians due to simplified procedures and high sensitivity and specificity of presurgical clinical diagnosis of commo...

Background and aim: The stroma of basal cell carcinoma (BCC) is rich in mast cells. Morpheaform BCC has been reported to contain much more mast cells than the other types of BCC, but their significance remains unknown. In this study we investigated the significance of mast cells related to BCC and possible relationship between increased number of mast cells and clinical and histological p...

various cell proliferation markers are used as diagnostic and prognostic tools in oral lesions. simultaneous evaluation of these markers can increase the precision of estimation of the proliferative status of different tissues. in this study we investigated the expression of pcna and ki-67 as markers of cell proliferation in 15 paraffin embedded samples of each dental follicle, dentigerous cyst...

P rostate cancer (PCa) is the second most common malignancy in men and if localized or confined to the gland at diagnosis, the choice of treatment includes surgery, radiation or watchful waiting. If and when the disease spreads, androgen blockade is effective but inevitably relapse occurs, resulting in incurable castrate-resistant PCa. Understanding the etiology of PCa will underpin the develop...

The aim of our study was an evaluation of the expression of cell proliferation markers (PCNA and Ki-67) in conjunctival and eyelid papillomas and squamous and basal cell cancers. A series of 9 cases of squamous cell cancer (SCC), 15 cases of basal cell cancer (BCC) and 43 cases of squamous cell papilloma (SCP) were assessed using the immunohistochemical method with monoclonal antibodies. PCNA o...

The pseudostratified epithelium of the mouse trachea and human airways contains a population of basal cells expressing Trp-63 (p63) and cytokeratins 5 (Krt5) and Krt14. Using a KRT5-CreER(T2) transgenic mouse line for lineage tracing, we show that basal cells generate differentiated cells during postnatal growth and in the adult during both steady state and epithelial repair. We have fractionat...

Various cell proliferation markers are used as diagnostic and prognostic tools in oral lesions. Simultaneous evaluation of these markers can increase the precision of estimation of the proliferative status of different tissues. In this study we investigated the expression of PCNA and Ki-67 as markers of cell proliferation in 15 paraffin embedded samples of each dental follicle, dentigerous cy...