We present evidence that Rb forms a repressor containing histone deacetylase (HDAC) and the hSWI/SNF nucleosome remodeling complex, which inhibits transcription of genes for cyclins E and A and arrests cells in the G1 phase of the cell cycle. Phosphorylation of Rb by cyclin D/cdk4 disrupts association with HDAC, relieving repression of the cyclin E gene and G1 arrest. However, the Rb-hSWI/SNF c...

In this paper we introduce a two-step Certified Reduced Basis (RB) method. In the first step we construct from an expensive finite element “truth” discretization of dimension N an intermediate RB model of dimension N N . In the second step we construct from this intermediate RB model a derived RB (DRB) model of dimension M ≤ N . The construction of the DRB model is effected at cost O(N) and in ...

the main goal of this paper is to propose a new practical method for hydrologic soil group estimation in surface runoff process based on geomorphology facieses and slop. the determination of cn based on this method can reduce the time and cost of project. in this research the upstream rivers of glinak watershed have been used as a case study to examine the efficiency of proposed method with a c...

A Rubidium high-frequency lamp is used as the pumping light source to excite Rubidium atoms in a sample cell. The pumping source light is filtered to transmit the D1 Rb line and polarizers are used to produce circular polarization. The circular polarization pumping mechanism selectively repopulates the sample cell ground state Rb Zeeman hyperfine levels away from thermal equilibrium populations...

Let A be a p. i. algebra with 1 in characteristic zero, satisfying a Capelli identity. Then the cocharacter sequence cn(A) is asymptotic to a function of the form ang n, where ∈ N and g ∈ Z. The second author conjectured that if A is any p. i. algebra in characteristic zero, with cocharacter sequence cn(A), then the asymptotic behaviour of this sequence should be given by cn(A) a · n · , where ...

It is well known that if Fis a field of characteristic zero and K=F(ax,..., ot„) is a finite algebraic extension of F, then K contains a primitive element, i.e. an element a such that F(oti,..., an) = F(a). Moreover, by means of Galois theory, it is possible to characterize those elements of the extension field which are primitive. In the case of finite differentially algebraic extensions the t...

The main goal of this paper is to propose a new practical method for hydrologic soil group estimation in surface runoff process based on geomorphology facieses and slop. The determination of CN based on this method can reduce the time and cost of project. In this research the upstream rivers of Glinak Watershed have been used as a case study to examine the efficiency of proposed method with a c...