BACKGROUND To determine the clinical relevance of different definitions of symptom remission for prediction of functional outcome in first-episode psychosis (FEP). METHODS One hundred forty-one individuals receiving treatment for an FEP at a specialized early intervention service had positive and negative symptoms and functional status rated every month over the first 2 years of treatment usi...

background and objective: this study was undertaken to assess the ability of standard urinalysis (ua) and hemocytometer white blood cell (wbc) counts for the diagnosis of urinary tract infection (uti) in patients with urinary symptoms. materials and methods: a total of 600 patients with symptoms of urinary tract infection were enrolled in this prospective study. standard ua, hemocytometer wbc c...

OBJECTIVE This study compared the effect of clozapine and haloperidol on positive and negative symptoms of schizophrenia and in patients with high levels of negative symptoms or the deficit syndrome. METHOD Patients were participants in a 15-site double-blind, random-assignment Veterans Administration trial comparing clozapine (N=205) and haloperidol (N=217) in hospitalized patients with refr...

BACKGROUND There is an increased interest in evaluating the impact of core symptoms of schizophrenia, both positive and negative, on functioning and burden of disease. OBJECTIVE To examine the extent to which prominent positive and prominent negative symptoms impact functional health, well-being, health-related quality of life (HRQoL), and family burden. METHODS Data on symptomatology, HRQo...

background: about 40%-60% of schizophrenic patients are resistant to ordinary treatment, which result from interference with different neurotransmitter systems in the process of disease. the aim of present study was to determine the effect of famotidine on several symptoms of schizophrenia which was nonresponsive to neuroleptic treatment.   methods: 30 schizophrenic patients previously nonrespo...

Background: Persistent depression is a chronic and refractory disorder associated with many mental comorbidities. The effects of traditional cognitive therapy, which is the most common treatment for depression, have been negligible. Objectives: The aim of this study was to assess the effectiveness of imagery-based cognitive therapy in patients with persistent depressive disorder. Methods: Th...

The 70 ev positive and negative ion mass spectra of ring-substituted nitrobenzenes were studied. The influence of the substituent group on the fragmentation modes of the molecular ions is discussed. The effect of pressure in the formation of negative ions was also studied. As expected, the ratio of fragment ions to negative molecular ions decreased with increasing pressure in ion source.