background: osteoporosis affects quality of life and may lead to depression in women. the purpose of this study was to evaluate the effects of zoledronic acid (za) treatment on depression and quality of life (q o l) in women with postmenopausal osteoporosis (po). materials and methods: a total of 88 newly diagnosed women with po were included in this study. all patients were treated with once-y...

Introduction: cyclooxygenase-2 (COX-2) is involved in pathogenesis of various tumors and possibly malignant skin tumors including malignant melanoma; however, there is not enough information about COX-2 expression in benign melanocytic lesions. In the present study we compared the expression levels of COX-2 in malignant melanoma and benign melanocytic lesions. Method: In this analytical study, ...

Objective(s): Several researchers have reported the relationship between infertility in male and varicocele for so many years but the implication of varicocele in female patients is remains elusive. Here, we aim to examine the effects of unilateral varicose ovarian vein on antioxidant capacity and oocyte quality of rat ovary after the experimental creation of varicocele in female rats. Material...

background and purpose: communication has become a core topic in nursing care and investigations on this topic could have a significant impact on increasing nursing quality services. the present study aims to evaluate the communication skills and nursing staff component focusing on emotional management, others' perception and self-expression. methods: this is a cross-sectional descriptive-...

Background: Infertility is defined as inability to achive pregnancy after one year of unprotected regular intercourse.it has been reported that about 10-15% of young couples suffer from infertility. There is evidence that antioxidants improve the fertility rate. Prunus cerasus contains strong antioxidant activity. The aim of this study is to evaluate Prunus cerasus effects on expression of prog...

objective: micrornas (mirnas) are single-stranded small rnas 18-25 nucleotides in length that regulate gene expression through translational inhibition and mrna cleavage. aberrant expression of mirnas contribute to several diseases. this has increased interest in profiling the expressions of these molecules. real-time quantitative pcr (rq-pcr) is a sensitive, quantitative technique for gene exp...

Background: Development of cloned bovine embryos. Materials and Methods: Oocytes collection,oocyte denudation, oocyte enucleation, nuclear transfer, electrofusion, reconstructed embryo activation, culture of reconstructed and IVF embryo,and treatment with SAH post fusion interval Treatment of reconstructed embryos with TSA for 12 hours after activation, preparation of somatic donor cells, donor...

Objectives: The current study evaluated the analgesic effects of bumetanide as an adjunctive in the management of neuropathic pain following spinal cord injury (SCI). The peripheral expression of Na-K-Cl cotransporter-1 (NKCC1) and K-Cl cotransporter-2 (KCC2) genes in polymorphonuclear lymphocytes (PMLs) was assessed as a possible biomarker indicating central mechanisms underlying the observed ...