نتایج جستجو برای: therapeutic antibody
تعداد نتایج: 505122 فیلتر نتایج به سال:
acceptance and commitment therapy (act) is a new development within behavioral therapy. its goal is to promote psychological flexibility. numerous studies show that suffering results when people attempt to avoid their inner experiences (experiential avoidance). this experiential avoidance often leads to rigid and inflexible behavior that also leads them to compromise their goals and what is imp...
ayurveda, the indian art of holistic medicine describes fasting in terms of upavasa and considers it as one among the depletion therapies. besides the extensive explanations on the preventive purports of fasting, the classics have explicitly explained and exemplified the therapeutic importance of fasting while treating different diseases and dealing with different stages of the diseases. feve...
conclusions it is better to remove the unused devices safely to prevent and decrease their possible complications. case presentation a 50-years-old woman, with a history of breast cancer, had a permcath emplacement in right subclavian vein for a course of chemotherapy. the treatment for cancer seemed to be successful and the permcath had remained in its position without complication, for a coup...
UNLABELLED Photoimmunotherapy is a highly cell-selective cancer therapy based on an armed antibody conjugate with a phthalocyanine-based photosensitizer, IR700. Photoimmunotherapy induces rapid and highly specific necrosis in targeted cancer cells after exposure to near-infrared (NIR) light. Cells not expressing the antigen are not affected. To date, photoimmunotherapy has been demonstrated onl...
Monoclonal antibodies (mAbs) and their derivatives are currently the fastest growing class of therapeutics. Even if naked antibodies have proven their value as successful biopharmaceuticals, they suffer from some limitations. To overcome suboptimal therapeutic efficacy, immunoglobulins are conjugated with toxic payloads to form antibody drug conjugates (ADCs) and with chelating systems bearing ...
The development of efficient strategies for generating fully human monoclonal antibodies with unique functional properties that are exploitable for tailored therapeutic interventions remains a major challenge in the antibody technology field. Here, we present a methodology for recovering such antibodies from antigen-encountered human B cell repertoires. As the source for variable antibody genes...
Objective(s): Program death 1 (PD-1)/ program death-ligand 1 (PD-L1) pathways, as the main inhibitory checkpoints, induce immunosuppression in the tumor microenvironment (TME). Despite the importance of inhibitor checkpoint receptor (ICR) blockers, their outcomes have been limited by the low immune response rate and induced acquired resistance. Pre-existing tumor-speci...
Radioimmunotherapy with 131I-labeled monoclonal immunoglobulins was studied using the Rauscher murine erythroleukemia. Tumor-specific monoclonal antibody, nonrelevant monoclonal antibody, F(ab')2 fragments, polyclonal gamma-globulin, and serum albumin were used as carriers of 131I. Therapeutic effects as measured by the reduction in splenomegaly were seen with all the radiolabeled proteins test...
The disease concept of Neuromyelitis Optica Spectrum Disorders(NMOSD) has undergone a significant change over the last two decades including detection Myelin Oligodendrocyte Glycoprotein(MOG) antibody in patients who are seronegative for aquaporin-4 antibody. Aquaporin-4 positive NMOSD is now regarded as an immune astrocytopathy. Conversely, MOG associated known to target myelin rather than ast...
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