mechanical thrombectomy has shown promising results in large vessel ischemic stroke, with recent large trials changing to guidelines worldwide. in this presentation, results from the five recent randomized trials will be discussed. there is an ongoing debate on the inclusion and exclusion criteria of mechanical thrombectomy. it can be done in large vessel occlusions, including up to m2 middle c...

Background & Aims: Ischemic postconditioning, conducted by a series of brief occlusion and release of the bilateral common carotid arteries, has neuroprotective properties in permanent or transient models of middle cerebral artery (MCA) occlusion but its delayed neuroprotective effects in the embolic model of stroke, especially in female rat, have not yet been reported and were investigated ...

Background: Clinical information about stroke in the vertebrobasilar territory has lagged behind that for anterior circulation syndrome. This is the first report from posterior circulation syndrome registry in Iran. Methods: Consecutive patients with brain infarction in vertebrobasilar territory admitted to Ghaem hospital, Mashhad were enrolled in a prospective study during 2006-2007. Diagnosis...

Background: Stroke is the third main cause of death and chronic disabilities in adults, which requires finding neuroprotective drugs to reduce its mortality and morbidity.  Objectives: To determine the efficacy of magnesium sulfate as an adjunctive neuroprotective agent in patients with stroke. Materials & Methods: This randomized double-blind clinical trial recruited 120 patients with acute ...

Introduction: Based on our previous findings, the treatment of stem cells alone or in combination with thyroid hormone (T3) and mild exercise could effectively reduce the risk of stroke damage in young mice. However, it is unclear whether this treatment is effective in aged or middle-aged mice. Therefore, this study designed to assess whether combination of Bone Marrow Stromal Cells (BMSCs) wit...

Cerebral ischemia causes death of millions people all over the world, annually and also suffering more people from neurological deficits and neuromuscular disorders. In our country, 250 to 300 people experience mild to severe stroke, daily. In this study we reviewed 120 original paper selected from PubMED database. Our keywords were erythropoietin, anti-inflammatory, stroke, neuropathy and cere...

background: the aim of this study is to determine the frequency of intracranial artery stenosis in patients with acute ischemic stroke in iran. methods: a total of 169 patients with acute ischemic stroke were eligible to participate and were enrolled in this study from january 2012 to february 2013. all the patients were admitted to the nemazee ‎hospital, affiliated to shiraz university of medi...

Сarotid atherosclerotic disease increase the risk of ischemic stroke, with various clinical manifestations from asymptomatic to fatal. Cerebral blood flow depends not only on degree stenosis, but also patency collateral tract, affecting severity picture. Criteria for hemodynamic significance carotid artery stenosis and, based them, indications surgical treatment have been developed. But there i...