Epilepsy is a chronic neurological disease which disrupts the neuronal electrical activity. One-third of patients are resistant to treatment with available antiepileptic agents. The use of herbal medicine for treating several diseases including epilepsy is on the rise. Therefore, further investigation is required to verify the safety and effectiveness of Phytomedicine in treating diseases. The ...

Epilepsy is a chronic neurological disease which disrupts the neuronal electrical activity. One-third of patients are resistant to treatment with available antiepileptic agents. The use of herbal medicine for treating several diseases including epilepsy is on the rise. Therefore, further investigation is required to verify the safety and effectiveness of Phytomedicine in treating diseases. The ...

Mitochondria are central for various cellular processes that include ATP production, intracellular Ca(2+) signaling, and generation of reactive oxygen species. Neurons critically depend on mitochondrial function to establish membrane excitability and to execute the complex processes of neurotransmission and plasticity. While much information about mitochondrial properties is available from stud...

Our aim is to design a model which demonstrates inhibitory and excitatory effects as observed in a neuronal network cultivated on a multielectrode array (MEA) neurochip.

Neuronal brain activity is assumed to be reflected by blood level oxygenation levels, also known as BOLD signal, measured with fMRI. A scan of the literature points both oxygen and carbon dioxide levels effects on The roles (O2 ; hypoxia/hypoxemia, hyperoxia) (CO2 hypocapnia, hypercapnia) in neuronal signal are complex still under investigation [1,2]. Inspiration while varying O2 CO2 air have b...