Vitiligo is a skin disease that has been known about for at least 5000 years, but little has been done to understand its causes or to evaluate possible treatment. It is not a painful condition and perhaps that is why it is often trivialized and left untreated. Vitiligo is characterized by depigmented areas of skin. There are several different theories One theory is that people develop antibodie...

BACKGROUND Patient-reported outcome measures are rarely used in vitiligo trials. The Vitiligo Noticeability Scale (VNS) is a new patient-reported outcome measure assessing how 'noticeable' vitiligo patches are after treatment. The noticeability of vitiligo after treatment is an important indicator of treatment success from the patient's perspective. OBJECTIVES To evaluate the construct validi...

So, what is vitiligo? Vitiligo a condition in which people lose the cells skin that give it color. These are called melanocytes. leaves affected individuals with white spots scattered across their skin. This article includes background information on structure. It then explores causes and treatment of vitiligo. Finally, we discuss impact vitiligo can have mental health.

Many therapeutic modalities are available for vitiligo treatment. However, there is a lack of consensus about methods that assess the treatment outcome of the disorder. Comparative studies of various treatments of vitiligo, relied until recently on subjective methods based on an approximate evaluation of the extent of depigmented areas. Recently objective modalities that could be used to assess...

Vitiligo is an acquired depigmentary skin disorder characterized by white maculae on the skin associated with social stigma. Vitiligo has major impact on the quality of life due its high cosmetic value, chronic nature of disease and long term ineffective treatments. Vitiligo patients suffer from low self-esteem and poor body image that affects their emotional and psychological well-being. To in...

BACKGROUND Vitiligo is a chronic depigmenting skin disorder which affects around 0.5-1% of the world's population. The outcome measures used most commonly in trials to judge treatment success focus on repigmentation. Patient-reported outcome measures of treatment success are rarely used, although recommendations have been made for their inclusion in vitiligo trials. This study aimed to evaluate...

Psychotic disorders have been observed in association with some autoimmune disorders. Moreover, autoimmune mechanisms have been recently considered in evaluation of schizophrenia spectrum disease managements. Vitiligo is one of the autoimmune diseases, but there is no report of vitiligo association with psychosis. We report three patients with vitiligo and schizophrenia spectrum disease that ar...

BACKGROUND Vitiligo is the most frequent depigmentation disorder of the skin and is cosmetically and psychologically devastating. A recently updated Cochrane systematic review 'Interventions for vitiligo' showed that the research evidence for treatment of vitiligo is poor, making it difficult to make firm recommendations for clinical practice. OBJECTIVES To stimulate and steer future research...