background: pancreatitis is a serious complication of endoscopic retrograde cholangiopancreatography (ercp) and may cause significant morbidity and even death. there is no effective prophylactic intervention for patients with average risk yet. this study aims to investigate preventive effect of aggressive hydration for post-ercp pancreatitis. materials and methods: in a double-blind controlled ...

Objective. To study the pathogenic feature of liver injury, activation of hepatic stellate cells, and dynamic expression of TGF-β1/TGF-β3 to reveal their role in liver injury induced by ConA. Methods. Mice were randomly divided into control group and ConA treatment group. ConA (20 mg/kg) was injected through vena caudalis in ConA treatment group; the controls received the same volume of saline ...

sperm selection techniques have became an important tool to improve sub fertile ejaculates. the main aim of this study was to assess the dynamics of motile sperm subpopulations of ejaculates from subfertile stallions subjected to density gradient centrifugation (dgc) involving a double layer colloid [dgc2], before and after storage for 24 and 48 hours. ejaculates from eight stallions with ferti...

Introduction: Similarities in the memory impairment between Alzheimer patients and scopolamine treated animals have been reported. In the present study, the possible role of α-adrenergic receptors of the dorsal hippocampus on scopolamine state-dependent memory in adult male Wistar rats was evaluated. Methods: The animals were bilaterally implanted with chronic cannulae in the CA1 regions o...

Eight female Sprague-Dawley rats were housed in isolated continuous 24-h/day environments under conditions of constant dim light and a rate-limited feeding schedule. Following 2 months of free-running activity, all animals were administered methamphetamine (MA) i.p. (2 mg/kg) once every 31 h for 24 injection cycles. Average wave forms of wheel-running activity showed that animals did not antici...

background: latrodectism, a syndrome caused by latrodectus genus, is one of the clinical problems that occur predominantly in north east of iran. nowadays antivenom therapy has become the most useful treatment for animal bites; however there is still a controversy about route and time of antivenom administration in spider bite. the aim of the present study was to determine the efficacy of speci...

introduction: recently, due to the special characteristics of 166ho and chitosan, 166ho-chitosan complex was developed for treatment of tumors such as hepatocellular carcinoma. this complex has been lately prepared with high radiochemical purity in our lab. the preclinical studies of the complex however should be performed to evaluate the tracer concentration in target and normal tissues before...

BACKGROUND AND AIMS Various additives have been evaluated for the purpose of enhancing quality of analgesia and prolonging duration of spinal anesthesia. This randomized, double-blind study was conducted to evaluate the efficacy of intravenous dexamethasone in spinal anesthesia. METHODS A total of sixty patients scheduled for lower segment cesarean section under spinal anesthesia were randoml...