Background: Diabetes mellitus as a chronic disease can cause fertility problems in male human population. In fact, it exerts sever damages in testicular tissue and subsequently reduces total number of normal sperms and semen volume. Therefore, this study is designed to evaluate the protective effect of Equisetum arvense extract on sperm quality, DNA damage and maturation in diabetic male mice. ...

Introduction: MicroRNAs have been reported as potentially valuable biomarkers for various ‎diseases, including diabetes, heart diseases, neurological diseases, and age-related diseases. The ‎present study aimed to investigate the effect of 8 weeks of intense intermittent exercise on the ‎expression of mir146a, blood sugar, insulin, and insulin resistance in the hippocampus of aged diabetic male...

The potential role of omega – 3 (ω-3) and omega - 6(ω-6) fatty acids on wound healing is of interest and controversial. In the present study, the effect of dietary intake of fish oil (ω-3 diet ) and corn oil (ω-6 diet) on skin wound healing has been investigated in rat. This experimental study was performed on four groups of male rats (one normal group and three diabetic groups). Diabetes was i...

background: nigella sativa (n. sativa) seeds are used to treat diabetes mellitus in traditional medicine. moreover, n. sativa oil has reduced the fasting blood glucose level in non-diabetic volunteers. objective: the present study was undertaken to explore the possible anti-hyperglycemic effect of n. sativa oil in type ii diabetic patients. methods: a randomized clinical trial was conducted in ...

Diabetic retinopathy is a preventable microvascular diabetic complication and a leading cause of vision loss. Retinal pigment epithelial cell apoptosis is an early event in diabetic retinopathy. Taurine is reportedly beneficial for diabetic retinopathy and is abundant in the fruit of Lycium barbarum (LB). We have investigated the effect of pure taurine and an extract of LB rich in taurine on a ...

Several epidemiological and clinical studies have indicated that the prevalence of psychiatric disorders is higher in diabetic patients than in the general population. In the present studies, we examined the behavioral changes in streptozotocin-induced diabetic rats, and investigated the effects of physical and psychological stress on the hippocampal BDNF levels and on the serotonin 2A (5-HT(2A...

Diabetic cardiomyopathy (DCM) is characterized by cardiac dysfunction and cardiomyocyte apoptosis. Oxidative stress is suggested to be the major contributor to the development of DCM. This study was intended to evaluate the protective effect of low molecular weight fucoidan (LMWF) against cardiac dysfunction in diabetic rats. Type 2 diabetic goto-kakizaki rats were untreated or treated with LMW...

Danhong Huayu Koufuye (DHK), a traditional Chinese prescription, is used to treat central retinal vein occlusion clinically. We previously reported that DHK prevented diabetic retinopathy (DR) in rats. Moreover, we found that it protected endothelial cells from hyperglycemia-induced apoptosis through antioxidation and anti-inflammation. Here, we investigated whether antioxidative and anti-infla...