Dry eye disease is a disorder in tear film physiology, which leads to various abnormal states of ocular surface cells. In the present study, we evaluated the potential usefulness of orally applied maqui berry (Aristotelia chilensis) extract and the constituent anthocyanin as a preventative intervention in dry eye. Tear secretion capacity was evaluated following the oral administration of maqui ...

the hawthorn fruits have been used as food and medicine for centuries. in the present study, pulp and seed extract of crataegus elbursensis rech. f. fruits belonging to the family rosaceae and native of northern part of iran were evaluated for the polyphenol contents, antiradical, antioxidant, and antibacterial activities. the total phenolic, flavonoid, and anthocyanin contents of methanolic pu...

Anthocyanin pigments in grape juice can coprecipitate with potassium bitartrate (KHT) crystals during cold stabilization, but factors that reduce these adsorptive losses are not well understood. We hypothesized that coprecipitation on a % w/w basis should be decreased at lower pH. In initial experiments, model juice solutions containing an anthocyanin monoglucoside extract and varying pH values...

Strawberry bioactive compounds are widely known to be powerful antioxidants. In this study, the antioxidant and anti-aging activities of a polyphenol-rich strawberry extract were evaluated using human dermal fibroblasts exposed to H2O2. Firstly, the phenol and flavonoid contents of strawberry extract were studied, as well as the antioxidant capacity. HPLC-DAD analysis was performed to determine...

The effects of anthocyanin-free aqueous extract Hibiscus sabdariffa petal on body weight gain, organ/body ratio and selected toxicological indices in cadmium intoxicated male rats were examined. When compared to cadmium-free extract-free control ,cadmium caused significant (P < 0.05) decreases prostate/body testis/body ratios .Prostatic acid phosphatase activity (only prostate) catalase acti...

Anthocyanins are secondary plant metabolites responsible for the blue, purple, and red color of many plant tissues. The phenolic structure of anthocyanins conveys marked antioxidant activity in model systems via donation of electrons or hydrogen atoms from hydroxyl moieties to free radicals. Dietary intakes of anthocyanins may exceed 200 mg/day, however, little is known about their antioxidant ...

In the present study, the question was addressed whether anthocyanins interfere with the topoisomerase I poison irinotecan in vivo. In vivo complexes of enzyme to DNA bioassay was used to detect irinotecan-induced stabilization of topoisomerase I/DNA complexes and single cell gel electrophoresis to determine DNA-strand-break induction in the colon of male Wistar rats. Furthermore, analysis of a...

An anthocyanin-rich extract, generated from açai (AEA), was investigated for its antioxidant properties and antiproliferative activity against C-6 rat brain glioma cells and MDA-468 human breast cancer cells. AEA has an ORAC value of 2589 lmoles trolox equivalents (TE)/g dried powder and a DPPH radical-scavenging activity of 1208 lmoles TE/g, suggesting that AEA is an exceptional source of natu...