Pseudomonas aeruginosa (Pa) is an opportunistic pathogen that threatens the health, especially in immunocompromised individuals. survives everywhere, including a shuttle of spaceflights. Survival and starvation Pa water probably increase or decrease degree pathogenicity virulence, but it not well discovered. To promote our understanding mechanisms long-term survival water, investigations on kin...

Objective: Carthamus tinctorius L. (Safflower) is a member of the asteraceae family which is used as a food additive but also has medicinal applications. This study investigated its effects on placental histomorphology and survival of mice neonates. Materials and Methods: Eighty Balb/C pregnant mice were randomly distributed into one control and three experimental groups (n=20). The control gr...

TASK-3, a two-pore-domain (K2P) potassium channel, has been implicated as important regulator for the effector function and proliferation of T-cells. Interestingly, TASK-3 has also a functional impact on tumor cells. Therefore, we sought to investigate whether TASK3 modulation might have a therapeutic potential for malignant gliomas by a variety of phenotypical and functional in vitro assays mi...

Objective(s): The goal of this research was to develop a mouse orthotopic liver transplantation (LTx) model from donor-after-cardiac-death (DCD) grafts. Materials and Methods: Mice were randomly assigned to the experimental group or the sham group. The mice in the experimental group were divided into three groups according to the warm ischemia time (WIT) of liver graft: normal LTx, WIT 30 minut...

objective: carthamus tinctorius l. (safflower) is a member of the asteraceae family which is used as a food additive but also has medicinal applications. this study investigated its effects on placental histomorphology and survival of mice neonates. materials and methods: eighty balb/c pregnant mice were randomly distributed into one control and three experimental groups (n=20). the control gro...

Frailty is defined as an age-related decline in physiological reserve and increased vulnerability to stress. As frailty a multifaceted condition, there no effective pharmacotherapy for it yet. Ninjin’yoeito (NYT) Kamikihito (KKT), traditional Japanese medicines (Kampo medicines), are promising treating conditions of including fatigue mental anxiety. However, their effects still unclear. In this...

Background: In some areas of Ramsar, a city in northern Iran, residents receive a much higher annual radiation exposure than is permitted for radiation workers. Induction of adaptive response in residents of Ramsar has been reported previously. In this study induction of such a response in short term exposure to high background levels of gamma radiation is investigated. Materials and M...

Background: The aim of this study was to evaluate the radioprotective capacity of some novel aminoalkylated dithiocarbamic acid potassium salts against γ-irradiation in mice. Materials and Methods: Eight compounds containing 2-aminoethyl-, 3- aminopropyl-, 4-aminobutyl-, 5-aminopentyl-, 6- aminohexyl-, 7-aminoheptyl-, 8-aminooctyl and 9- aminononyl of dithiocarbamate derivatives were prepared. ...

the methanolic extracts of indigofera aspalathoides (meia) and wedelia calendulaceae (mewc) were evaluated for their anticancer activity against ehrlich ascites carcinoma (eac) in swiss albino mice. on day 1, the extract of indigofera aspalathoides at a dose of 250 and 500 mg/kg body weight and the extract of wedelia calendulaceae at a dose of 250 and 500 mg/kg body weight were administered ora...