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insurers have in the past few decades faced longevity risks - the risk that annuitants survive more than expected - and therefore need a new approach to manage this new risk. in this dissertation we survey methods that hedge longevity risks. these methods use securitization to manage risk, so using modern financial and insurance pricing models, especially wang transform and actuarial concepts, ...
legal establishment of court is the birth of social life; each person should define him/herself against others offence or violation. when a society forms and the legal character appears, the thought of society refers to a person name prosecuting attorney who is the president of the court for defending his/her rights. prosecuting attorney remindterms such as court, crime and punishment. accordi...
The writing committee for the International Adjuvant Lung Cancer Trial (IALT) (Rodrigo Arriagada, M.D., Instituto de Radiomedicina, Santiago, Chile; Bengt Bergman, M.D., Sahlgrenska Hospital, Göteborg, Sweden; Ariane Dunant, M.S., Thierry Le Chevalier, M.D., and Jean-Pierre Pignon, M.D., Ph.D., Institut Gustave-Roussy, Villejuif, France; and Johan Vansteenkiste, M.D., Ph.D., University Hospital...
Cancer is a major public health problem both in our country and worldwide due to its disease burden, fatality and tendency for increased incidence (Akgun Sahin et al., 2013). Globally, cervical cancer is the second most prevalent cancer and third most common type of cancer after breast and lung cancers among women (Sogukpinar et al., 2013). The global burden of cervical cancer is disproportiona...
Noncoding RNA for personalized prostate cancer treatment: utilizing the ‘dark matters’ of the genome
2017 Prostate cancer is the most commonly diagnosed cancer in men in western countries, with significant health impact. Clinically, it is complicated with the lack of biomarkers and effective treatments for aggressive disease, particularly castration-resistant prostate cancer. Although we have gained much insight into the biology of prostate cancer through studying protein-coding genes, they re...
It is known that Tardos’s collusion-secure probabilistic fingerprinting code (Tardos code; STOC’03) has length of theoretically minimal order with respect to the number of colluding users. However, Tardos code uses certain continuous probability distribution in codeword generation, which creates some problems for practical use, in particular, it requires large extra memory. A solution proposed ...
Methods We carried out a SR of advanced prostate cancer (PC) trials published over the period 2008-2013 (reported separately) and then reviewed the corresponding trials registry entries for the studies included in the SR. Clinicaltrials.gov NCT registration numbers were extracted from the papers where available. Where an NCT number was not available, the registry was searched for the study. A t...
BACKGROUND The proportion of the newly graduated pediatric workforce that becomes hospitalists has been increasing slightly over the past decade. However, it is unknown what proportion of those who accept hospitalist positions as their first job intend to remain in the field longer term. This is important to workforce projections regarding the magnitude of those who will function in this role. ...
now-a-days graphic design plays a major role in influencing culture, society, business, and customers, in such a way that one could look upon every individual as a potential customer. graphic designers seek to identify customers needs and find an intelligent solution for them. correct identification and understanding of those needs is the first step towards achieving ones goals. marketing knowh...
what miller wants is a theatre of heightened consciousness. he speaks of two passions in a man, the passion to "feel" and the passion "know". he belives that we can have more of the latter. he says: drama is akin to the other inventions of man in that it ought to help us know more and not merely to spend our feelings. the writing of the crucible shows us that he is trying to give more heightene...
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