mycobacterium tuberculosis, the main cause of tuberculosis (tb), has still remained a global health crisis especially in developing countries. tuberculosis treatment is a laborious and lengthy process with high risk of non compliance, cytotoxicity adverse events and drug resistance in patient. recently, there has been an alarming rise of drug resistant in tb. in this regard, it is an unmet need...

Many important processes affecting the earth’s climate are determined by physical properties of seawater. In addition, desalination seawater is a significant source drinking water for human population living in coastal areas. Since governing these depend on molecular interactions among its components, deeper knowledge at level would contribute to better understanding phenomena. However, strong ...

سابقه و هدف: امروزه با گسترش فعالیت واحدهای صنعتی، غلظت آلاینده­ ها در هوا افزایش یافته انسان­ از طریق تنفس، بلعیدن جذب پوستی معرض آن­ها قرار می­ گیرند. میان تمام آلاینده ­ها، فلزات سنگین به دلیل ماهیت سمی خود بسیار مورد توجه متخصصان زیست ­محیطی گرفته ­اند. بالای محیط ­زیست، می ­تواند خطر اثرات نامطلوب بر سلامتی انسان را دهد. شهرک صنعتی ناجی زنجان ریخته ­گری مس آلیاژهای آن، ­عنوان یکی منابع انت...

The IL-1β play a major role in inflammatory disorders and IL-1β production inhibitors can be used in the treatment of inflammatory and related diseases. In this study, quantitative relationships between the structures of 46 pyridazine derivatives (inhibitors of IL-1β production) and their activities were investigated by Multiple Linear Regression (MLR) technique Stepwise Regression Method (ES-S...