conclusions this study showed that ifnβ-1a decreased oxidant impacts in ms patients, but had no influence in improving mitochondrial dysfunction. results in the patients group (30 patients), a significant difference was observed in their measured biochemical factors in comparison to the control group (p = 0.001), however, after six months of using ifnβ-1a, only mda was shown in the main (p = 0....

OBJECTIVE This study was to assess liver involvement in multiple myeloma with the aid of liver function tests. MATERIALS AND METHODS A hospital based retrospective study was undertaken using data retrieved of multiple myeloma from the register maintained in the Department of Biochemistry of the Manipal Teaching Hospital, Pokhara, Nepal between 1st January, 2007 and 28th February, 2012. We col...

BACKGROUND In acute pancreatitis, oxygen free radicals (OFRs) and cytokines have been shown to play a role in the failure of pancreatic microcirculation and the development of local tissue damage. We studied the effects of trimetazidine (TMZ), a potent antioxidant and anti-ischemic agent, on acute pancreatitis. METHODS Rats were randomized into 3 groups: a control group (n = 15), a study grou...

Objective(s): Diazinon (DZ) is an organophosphate pesticide that induces oxidative damage in different organs. The aim of this study was to compare the effectiveness of nanomicelles containing curcuminoids (NCUR) and natural curcumin (CUR) in attenuating the oxidative damage induced by DZ in male rats. Materials and Methods: After a single intraperitoneal (IP) injection of DZ (100 mg/kg), the r...

Serum lactate dehydrogenase (LDH) level is predictive of prognosis in various malignancies. Nevertheless, the association between the prognosis of patients with advanced triple-negative breast cancer (TNBC) and LDH is not well understood. This explorative and retrospective study was conducted to clarify the issue. We found that abnormal baseline LDH levels (> 250 IU/L) were significantly associ...

Today, human effects due to industrial development and population increase caused water ecosystems be polluted by various pollutant such as heavy metals. Serum biochemical parameters are widely used in blood analysis these suitable indicators for monitoring physiological changes fish. Hence, the aim of present study waterborne copper on serum glucose, total protein, albumin triglyceride levels ...

COVID-19 an ongoing pandemic has high transmission and mortality rate gets the attention of researchers to focus on disease. The burden disease health care system focuses impacts hematological biochemical parameters. This study aimed laboratory indicators that fluctuate in COVID-19. single-center cross-sectional pathology department POF hospital Wah Cantt from August 2021 December 2021. Three h...