نتایج جستجو برای: binding protein 2 cabp2

تعداد نتایج: 3623211  

Human serum albumin (HSA) is the most abundant protein in the blood plasma. Molecular dynamics simulations of subdomain IIA of HSA and its complex with salicylic acid (SAL) were performed to investigate structural changes induced by the ligand binding. To estimate the binding affinity of SAL molecule to subdomains IB and IIA in HSA protein, binding free energies were calculated using the Molecu...

Journal: :physical chemistry research 0
nasrin - sohrabi assistant professor of phys. chemistry,academic member,payame noor university,shahin shahr,isfahan, iran nahid rasouli department of chemistry, payame noor university (pnu), 19395-3697, tehran, i.r.iran marziyeh raissi department of chemistry, payame noor university (pnu), 19395-3697, tehran, i.r.iran

abstractinteraction of ni complex(salen= n, n´-ethylene bis(salicylideneimine)) with hen egg-white lysozyme (hewl) was studied by absorption spectroscopy, competitive binding study and thermal denaturation study. the protein binding affinity of ni complex was found to be (3.0×103m−1). the binding plot obtained from the absorption titration data gives a binding constant of 2.4 (± 0.3)×103 m-1. i...

Journal: :Journal of medical microbiology and infectious diseases 2022

Evolutionary Analysis of Mammalian ACE2 and the Key Residues Involved in Binding to Spike Protein Revealed Potential SARS-CoV-2 Hosts

Abbas Shirdel, Abdol Rahim Rezaee Akram Beyk yazdi Hassan Rahimi Houshang Rafatpanah Ian V Hutchinson Mahmoud Reza Azarpajooh

Introduction Genetic background has known to be associated with the outcome of human T cell lymphotropic virus (HTLV) type I infection. In The present study we investigate the association between GM-CSF gene polymorphisms with the outcome of HTLV-I infection. Materials and Methods We analyzed 3 single-nucleotide polymorphisms in the promter region of granulocyte macrophage colony stimulating...

طباطبائی فرPhD , محمدامین, فتاحی M‏Sc , فاطمه, هاشم زاده چالشتری, مرتضی, حسینی پورMD , اعظم , رضائیانBSc ، , فاطمه , صالحی چالشتری M‏Sc , حمیدرضا , صالحی چالشتری M‏Sc , احمدرضا ,

سابقه و هدف: ناشنوایی مادرزادی متداولترین نقص حسی در انسان است. شایعترین جهشهای ژنی دخیل در این بیماری، جهش های ژن GJB2 و بعد از آن جهشهای ژن SLC26A4 می باشند. به دنبال گزارشی که برای اولین بار در جهان مبنی بر دخالت ژن CABP2 در ایجاد ناشنوایی گزارش گردیده است، مطالعه حاضر با هدف بررسی این جهش در بیماران ایرانی مبتلا به ناشنوایی انجام شده است.مواد و روشها: این مطالعه مقطعی بر روی 253 نمونه مبتلا...

Journal: :iranian journal of basic medical sciences 0
abbas shirdel internal medicine department, ghaem hospital, mashhad university of medical sciences, mashhad, iran houshang rafatpanah immunology research centre, buali reserch institute, mashhad university of medical sciences, mashhad, iran centre for integrated genomic medical research (cigmr), the university of manchester, manchester, uk hassan rahimi internal medicine department, ghaem hospital, mashhad university of medical sciences, mashhad, iran abdol rahim rezaee immunology research centre, buali reserch institute, mashhad university of medical sciences, mashhad, iran mahmoud reza azarpajooh neurology department, ghaem hospital, mashhad university of medical sciences, mashhad, iran

introduction genetic background has known to be associated with the outcome of human t cell lymphotropic virus (htlv) type i infection. in the present study we investigate the association between gm-csf gene polymorphisms with the outcome of htlv-i infection. materials and methods we analyzed 3 single-nucleotide polymorphisms in the promter region of granulocyte macrophage colony stimulating fa...

Journal: :journal of paramedical sciences 0
kamal mirzaie badrabadi department of computer engineering, maybod branch, islamic azad university, maybod, iran mehdi mirzaie department of computational biology, faculty of high technologies, tarbiat modares university, tehran, iran

protein structural flexibility is important for catalysis, binding, protein design, and allostery. some simple methods have recently been introduced to compute protein flexibility directly from the protein structure without any mechanical models. for example the atomic mean square displacement (or b-factor) is related to the number of neighboring atoms. the protein structure can be modeled as a...

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