Epidermal growth factor receptor (EGFR) has been implicated as a factor indicating tumour progression or as a prognostic factor in non-small cell lung cancer (NSCLC), in which its overexpression is often detected. The usefulness of identifying EGFR in serum from patients with NSCLC is controversial. This study was designed to identify serum EGFR levels in patients with NSCLC and to evaluate the...

objective(s): the aim of the present study was to evaluate the effect of quercus brantii galls extract on the rat skin burn wound healing. materials and methods: ethanol extract of the galls of q. brantii was used to treat the induced burn wounds on the back of 32 wistar rats divided into 4 groups. the groups were treated by placebo, 1%, 2% and 4% concentration gall extract gels for 14 days and...

Objective(s): The present study sought to evaluate the beneficial effects of histidine (His) on oxidative stress, tumor necrosis factor alpha (TNF-α), renal histological alterations and anti-oxidant enzymes gene expressions in type 2 diabetic rats.Materials and Methods: Streptozotocin/nicotinamide (STZ/NA) induced diabetic rats were used...

Background: Imedeen tablets are revolution in anti-aging skincare. This tablets contains Biomarin complex (rich in natural proteins and Marin polysaccharides) and Lycophence GS complex rich in grape seeds extract and lycophence antioxidant,helps to give the skin protection against both direct and indirect damage that caused by free radicals.Cyclophosphamide as an anticancer agent has been known...

A subset of non-small cell lung carcinoma (NSCC) harbor active mutations of epidermal growth factor receptor (EGFR). In these, EGFR tyrosine kinase inhibitors (EGFR-TKIs) are recommended as the first-line treatment. Though drug resistance is inevitable, histological transformation to small cell lung carcinoma (SCLC) is a rare mechanism for acquired resistance. Here we report one such rare case ...

Pseudolymphomas of the skin are a heterogeneous group diseases manifested by benign lymphoid infiltrates that clinically and/or histologically mimic lymphoma.
 The pseudolymphomas includes actinic reticuloid, lymphocytoma skin, true pesvdolymphoma, postscabious lymphoplasia, lymphocytic reactions to insect bites, etc. diagnosis pseudolymphoma is based on anamnesis data (the presence provok...

The aim of this study was to evaluate CD44v6 protein expression and its prognostic value of CD44v6 in ovarian carcinoma. The expression of CD44v6 was analyzed in 62 patients with ovarian carcinoma by immunohistochemical method. The data obtained were analyzed by univariate and multivariate analyses. The present study clearly demonstrates that tumor tissues from 41 (66.1%) patients showed positi...

The classification of chronic hepatitis introduced in 1968 is still current, but has been modified. The concept of bridging hepatic necrosis has been incorporated, and is recognised as an important feature of both acute and chronic aggressive (active) hepatitis (CAH). In the pathogenesis of the latter, piecemeal necrosis is, however, thought to be the more important factor. The histological pic...

littoral cell angioma is a splenic vascular tumor of splenic sinus lining cells that is considered benign in general. this report describes a case of littoral cell angioma with no malignant histological features. the lesion is composed of anastomosing vascular channels resembling splenic sinus; they are lined by endothelial cells which show mitotic activity very rare. immunohistochemically, the...