نتایج جستجو برای: methamphetamine abuse

تعداد نتایج: 73234  

Ali Ghabeli-Juibary Fariborz Rezaietalab Meisam Aghaee Mohammad Farzadfard, Mohsen Foroughipour,

Background: Peripheral nervous injury and neuromuscular complications from methamphetamine abuse has not been reported. The mechanism is not yet identified. Methods: Eight patients with lower extremity weakness following methamphetamine abuse were reported during December 2009 to May 2010. Results: Patients presented with lower extremity weakness. All patients were co-abusers of methamphetami...

Journal: :Journal of leukocyte biology 2016
Uma Sriram Jonathan M Cenna Bijayesh Haldar Nicole C Fernandes Roshanak Razmpour Shongshan Fan Servio H Ramirez Raghava Potula

The novel transmembrane G protein-coupled receptor, trace amine-associated receptor 1 (TAAR1), represents a potential, direct target for drugs of abuse and monoaminergic compounds, including amphetamines. For the first time, our studies have illustrated that there is an induction of TAAR1 mRNA expression in resting T lymphocytes in response to methamphetamine. Methamphetamine treatment for 6 h ...

ژورنال: اعتیاد پژوهی 2013
سیه جانی, لیلی, اورکی, محمد , زارع, حسین ,

Introduction: The aim of this study was to investigate relation between sustained attention disorders and lenght of Methamphetamine abuse. Method: 200 Methamphetamine abusers (males and females) of ages 20-40 who were recruited through residential rehabilitation treatment, selected through random available sampling. To evaluate function of sustained attention Continuous Performance Test was tak...

Journal: Addiction and Health 2015

Background: The abuse of narcotic drugs and psychotropic substances such as amphetamines and ecstasy has had a growing trend. Tachycardia, increased blood pressure, hallucinations, panic attacks, and psychosis are the negative effects of methamphetamine abuse. The present study aimed to assess psychiatric disorders associated with methamphetamine-induced psychotic disorder. Methods: This cross-...

Journal: :The Journal of pharmacology and experimental therapeutics 2016
Lisa R Gerak Gregory T Collins Charles P France

Stimulant abuse is a serious public health issue for which there is no effective pharmacotherapy. The serotonin2C [5-hydroxytryptamine2C (5-HT2C)] receptor agonist lorcaserin decreases some abuse-related effects of cocaine in monkeys and might be useful for treating stimulant abuse. The current study investigated the effectiveness of lorcaserin to reduce self-administration of either cocaine or...

2015
Mahin Eslami-Shahrbabaki Alireza Fekrat Shahrzad Mazhari

BACKGROUND The abuse of narcotic drugs and psychotropic substances such as amphetamines and ecstasy has had a growing trend. Tachycardia, increased blood pressure, hallucinations, panic attacks, and psychosis are the negative effects of methamphetamine abuse. The present study aimed to assess psychiatric disorders associated with methamphetamine-induced psychotic disorder. METHODS This cross-...

2006
Nora D. Volkow

Abuse Impact the HIV/AIDS Epidemic? D rug abuse and addiction have been inextricably linked with HIV/AIDS since the beginning of the epidemic. While intravenous drug use is well known in this regard, less recognized is the role that drug abuse plays more generally in the spread of HIV— the virus that causes AIDS—by increasing the likelihood of highrisk sex with infected partners. This is becaus...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2007
Chitra D Mandyam Sunmee Wee Amelia J Eisch Heather N Richardson George F Koob

Psychostimulant abuse produces deficits in prefrontal cortex (PFC) function, whereas physical activity improves PFC-dependent cognition and memory. The present study explored the vulnerability of medial PFC (mPFC) precursor proliferation and survival to methamphetamine self-administration and voluntary exercise, factors that may have opposing effects on mPFC plasticity to facilitate functional ...

2018
Suneerat Yangyuen Manop Kanato Udomsak Mahaweerawat

Objectives To identify the associations of characteristics of the neighborhood environment with substance abuse among clients receiving treatment for drug abuse in Thailand. Methods A cross-sectional study was conducted of 1128 drug addicts from 28 neighborhoods who were receiving treatment at all 7 compulsory drug detention centers in Thailand. A trained interviewer conducted structured inte...

Journal: :NeuroImage 2008
Joanna S. Fowler Nora D. Volkow Jean Logan David L. Alexoff Frank Telang Gene-Jack Wang Christopher Wong Yeming Ma Aarti Kriplani Kith Pradhan David Schlyer Millard Jayne Barbara Hubbard Pauline Carter Donald Warner Payton King Colleen Shea Youwen Xu Lisa Muench Karen Apelskog

Methamphetamine is one of the most addictive and neurotoxic drugs of abuse. It produces large elevations in extracellular dopamine in the striatum through vesicular release and inhibition of the dopamine transporter. In the U.S. abuse prevalence varies by ethnicity with very low abuse among African Americans relative to Caucasians, differentiating it from cocaine where abuse rates are similar f...

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