نتایج جستجو برای: process targeting
تعداد نتایج: 1443405 فیلتر نتایج به سال:
this study considers the level of increase in customer satisfaction by supplying the variant customer requirements with respect to organizational restrictions. in this regard, anp, qfd and bgp techniques are used in a fuzzy set and a model is proposed in order to help the organization optimize the multi-objective decision-making process. the prioritization of technical attributes is the result ...
in literature about inflation targeting, main factor is interest rate. in new surveys, price of some assets as housing is important in inflation targeting. iran inflation targeting is based on money changes and is not based on interest rate and housing price. in this paper, we want to survey problems of wrong policy of iran policy makers. we reveal that, using rate of deposit profit and growth ...
Anticancer drugs that target protein kinases include small molecule inhibitors and monoclonal antibodies. Feedback loops and cross talk between signaling pathways impact significantly on the efficacy of cancer therapeutics, and resistance to targeted agents is a major barrier to effective treatments. Increasingly, therapies are being designed to target multiple kinase pathways. This can be achi...
Hfq-binding small RNAs (sRNAs) in bacteria modulate the stability and translational efficiency of target mRNAs through limited base-pairing interactions. While these sRNAs are known to regulate numerous mRNAs as part of stress responses, what distinguishes targets and non-targets among the mRNAs predicted to base pair with Hfq-binding sRNAs is poorly understood. Using the Hfq-binding sRNA Spot ...
در سالهای اخیر دارو رسانی هدفمند با استفاده از نانو ذرات دارای عوامل ضد سرطان بدلیل دارا بودن توانایی منحصر بفرد در تجمع در محل تومور بسیار مورد توجه قرار گرفته است. از مشخصات بارز نانو داروها می توان به افزایش قدرت نفوذ و طول اثر دارو در بافت سرطانی اشاره نمود. گزینش مناسب سلولهای سرطانی توسط داروهای ضد سرطان مهمترین مشکلی است که در شیمی درمانی وجود دارد. در این راستا داروهای ضد سرطان نه تنها ...
Bacteria produce a wide range of exopolysaccharides which are synthesized via different biosynthesis pathways. The genes responsible for synthesis are often clustered within the genome of the respective production organism. A better understanding of the fundamental processes involved in exopolysaccharide biosynthesis and the regulation of these processes is critical toward genetic, metabolic an...
The identification and validation of targets for therapeutic drugs lies at the very heart of pharmacological research. Angiogenesis, or more specifically tumour initiated growth of new vessels, has been an active area of cancer research for several years. Indeed, there are currently more drugs in cancer clinical trials that are anti-angiogenics than those that fit into any other mechanistic cat...
In 2019, a new coronavirus (COVID-19) was discovered in Wuhan, China, which soon spread all over the world. The main hallmark of the disease includes fever, diarrhea, vomiting, and dry cough with dyspnea in half of the patients and acute respiratory distress syndrome (ARDS). Currently, no definitive treatment or prevention therapy exists for COVID-19 but scientists and researchers all over the ...
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