BACKGROUND Every year, millions of people are exposed to avoidable, life-threatening risks through the trans-fusion of unsafe blood. AIM To determine the survival time of Treponema pallidum in banked donor blood. MATERIAL AND METHODS Two groups of male Wistar rats (group A and B) were inoculated intratesticularly with 0.5ml of artificially infected donor blood (final density of Nichols trep...

* Corresponding Author: Tel: +9851138763852 Fax: +9851138763852 [email protected] Dear editor In recent years, the number of scientific research papers of Iranian scientists has substantially grown in national and international journals that indicates particular attitude of Iranian scientific community to the development of knowledge in different fields. Moreover, improvement of qualit...

Species independence of brain tissue binding was assessed with a large number of structurally diverse compounds using equilibrium dialysis with brain homogenates of seven species and strains (Wistar Han rat, Sprague-Dawley rat, CD-1 mouse, Hartley guinea pig, beagle dog, cynomolgus monkey, and human). The results showed that the fractions unbound of the seven species and strains were strongly c...

the purpose of this study was to investigate the effect of feeding dietary soy protein and soy protein supplemented with methionine on lipids and lipoproteins content of blood in wistar rats. sixteen male and 16 female wistar rats with the initial live weight of 116 ± 6.3 and 115.8 ± 6.8 grams respectively, were fed by the isocaloric and isonitrogenous diets containing casein (20%), soy protein...

The prevalence of type 2 diabetes mellitus (T2DM) and hypertension has markedly increased worldwide. The purpose of the present study was to examine the effects of a high-salt intake on the systolic blood pressure (SBP) and vascular responses in WBN/Kob-Leprfa/fa (WBKDF) rats, a new spontaneous animal model of T2DM. Male WBKDF rats and age-matched Wistar rats at 6 weeks of age were each divided...

In our studies with spontaneously hypertensive (SHR), Wistar-Kyoto (WKY), and Wistar rats, we observed normotensive WKY rats with cardiac hypertrophy determined by a greater left ventricular (LV) mass (LVM)-to-body weight (BW) ratio (LVM/BW) than that of normotensive Wistar rats. Thus we compared the following parameters in SHR, WKY, and Wistar rats: LVM/BW, cell capacitance as index of total s...

The material presented here is a result of histological examination of the ovaries of 34 rats from the Wistar series, which were 900 days of age or older. Of this group, 20 were 900 days or slightly older, 10 were 1,000 days or slightly older, and 4 were 1,100 days or more old. For comparison, tissues of t5 female rats of this series ranging between 600 and 900 days, were examined. The animals ...

Protein kinase C (PKC) is a family of protein kinases controlling protein phosphorylation and playing important roles in the regulation of metabolism. We have investigated expression levels of PKC isoforms in pancreatic islets and liver of diabetic Goto-Kakizaki (GK) rats with and without insulin treatment to evaluate their association with glucose homeostasis. mRNA and protein expression level...