Neuroinflammation mediated by microglia cells plays a critical role in the development of Alzheimer's disease. To identify novel natural neuroinflammation inhibitors, a bioactivity-guided phytochemical research was performed on the traditional Chinese medicine "Awei", that exhibited a significant inhibitory effect on nitric oxide production in over-activated microglia cells. The research identi...

Methanolic extract of 15 Iranian medicinal plants were prepared and tested for their cytotoxic activities against three cancer cell lines (MCF7, HepG2, WEHI164) and one normal cell line (MDBK). Some plants showed cytotoxic activities. The extract of Ferula szowitsiana root, which proved to be the most active, was chosen for further phytochemical studies. The major compounds of the most potent a...

Background: Some medicinal plants can stimulate growth in poultry. Objective: To compare the effects of dietary addition virginiamycin antibiotic and galbanum plant (Ferula gummosa) on performance, carcass characteristics, immune system, blood factors broiler chickens. Methods: A total 250 one-day-old male Ross 308 chickens were randomly assigned to five treatments with replicates (10 birds per...

Objective: Cervical cancer is the second most common type of cancer among women, worldwide; and for treatment of this type of cancer radiotherapy is commonly used. Ferula gummosa Boiss(“Barije” in Persian, from the family Apiaceae), (F. gummosa), is an extremely precious medicinal plant which naturally grows throughout the Mediterranean and Central Asia and is a native plant in Iran. The presen...

Xinjiang, a region of high salinity and drought, is a host to many arid and semi-arid plants. Many of these plants including Ferula spp. have indigenous pharmaceutical histories. As many of the medicinal properties of plants are in tandem with the associated microorganisms residing within the plant tissues, it is advisable to explore the endophytic potential of such plants. In the present study...

demographic toxicology is a common method for investigation on the sub lethal effects of pesticides on natural enemies. the side effects of plant extracts from root of madder (rubia tinctorum l.), seeds of dill (aniethum graveolens l.) and seeds of galbanum (ferula gummosa boiss.) in comparision with thiamethoxam were evaluated on life table parameters of c. carnea as agonoscena pistaciae preda...

Effect of hexane extract of Ferula jaeschkeana has been studied on the histological and biochemical constituents of the uterus of ovariectomized rats. Its administration caused remarkable increase in the height of luminal epithelium and the number of uterine glands. Its per se treatment also caused significant increase in the glycogen and protein contents and the activity of acid and alkaline p...