Low dose methotrexate (5-25 mg/week) represents a major therapeutic advance in the management of RA in the last decade. Its established efficacy has led to it being used as the lead comparator drug in slow acting anti-rheumatic drug (SAARD) trials, to its increasing use in early disease, and to its inclusion in many drug combinations currently being evaluated. It seems to be the best tolerated ...

BACKGROUND Colorectal cancer (CRC) is the third most common malignancy in Iran. Limited data are available on knowledge and barriers in regard to CRC and screening tests in Iran. The aim of the study was to characterize knowledge, practice, and barriers toward CRC and its screening tests among an Iranian at-risk population. METHODS This cross-sectional study was conducted with participation o...

ewe abortion and neonatal mortality are serious problems to sheep farmer. the objective of this paper was to report isolation of erysipelothrix rhusiopathiae from aborted fetuses in a flock in tehran, iran. abortion occurred in 10% of ewes in the flock. the fetuses were well developed and pinpoint, necrotic-like lesions were recorded on the placental cotyledons, whilst the inter -cotyledonary a...

The determination of heavy metal ions, such as nickel, in environmental and biological samples is very importance and can hardly be overemphasized because they have undoubtedly a serious potential hazard to the human organism. Nickel was long thought to be essential to plants and some domestic animals[1], but not considered to be a metal of biological importance until 1975, when Zerner discover...

Background: The outbreak of COVID-19 has caused a devastating pandemic scenario in the world. mortality rate increased and new socio-economic challenges are emerging. Millions gloves, gowns, face masks, shields used daily to prevent airborne transmission facilitate treatment COVID-19. Mismanagement these wastes can lead concerns due their contamination potential. A comprehensive plan improve ma...