The health benefit of coffee consumption mainly depends on chlorogenic acid (CGA), one its major active phenolic constituent. CGA have several biological properties like anticancer, antihypertensive, hepatoprotective, neuroprotective, renoprotective, antimicrobial etc. It is assumed that different forms contains amount CGA. In this regards, we developed and validated a simple cost effective chr...

Nephrotoxicity is the major limitation for the clinical use of cisplatin as an anti-tumoural drug. Intracellular effects of cisplatin cause tubular damage and tubular dysfunction with sodium, potassium, and magnesium wasting. Renoperotective strategies against cisplatin are classified on 8 targets: 1) Decrease of cisplatin uptake by renal cell, 2) Inhibition of cisplatin metabolism, 3) Blocking...

the world hypertension day celebrates 17 th of may of every year by concentrating on an important global health subject. for world hypertension day (whd) 2014, they have chosen “know your blood pressure “as the theme. chronic kidney disease is a worldwide public health puzzle and hypertension is one the most important cause of damage to the kidneys. in fact by improved screening, diagnostic eff...

Saffron petal is the main by-product of saffron processing which produced at high level but it is not applied and thrown out. Saffron petal is containing of several compounds such as mineral agents, anthocyanins, flavonoids, glycosides, alkaloids and kaempferol. As saffron petal is cheaper and produces in large amounts compared to saffron stigma, so, it can be considered as an appropriate sourc...