Objective: To analyze the expression and clinical significance of miRNA-495 in peripheral blood patients with acute myeloid leukemia. Methods: Fifty-six leukemia 56 healthy controls were selected. Fasting venous was drawn centrifuged, plasma collected. The target miRNA directly amplified reverse transcribed into cDNA. miR-495 detected by qRT-PCR. Results: level newly diagnosed (AML [ND]) relaps...

http://bmj.com/cgi/content/full/326/7387/495 Updated information and services can be found at: These include: References http://bmj.com/cgi/content/full/326/7387/495#otherarticles 3 online articles that cite this article can be accessed at: http://bmj.com/cgi/content/full/326/7387/495#BIBL This article cites 14 articles, 2 of which can be accessed free at: Rapid responses http://bmj.com/cgi/ele...

Randomized algorithm analyses normally assume access to a sequence of unbiased truly random bits. Unfortunately, it is not always easy to generate random bits with this property. Sources of randomness often are biased in one way or another. Is it possible to use an biased source of randomness to produce an unbiased sequence of random bits? To word it more formally, suppose we are given a biased...

MicroRNAs are involved in tumor initiation and progression by regulating oncogenes and tumor suppressor genes. Here we found that miR-495 are lower in clinical ESCC tissues than in adjacent non-tumor tissues. Moreover, the lower miR-495 expression correlated with increased lymph node metastasis (LNM), invasion and TNM stage. miR-495 overexpression predicted a favorable outcome in ESCC patients....

a micropaleontological study has been carried out on the samples collected from the sarv abad section, the oldest and only known jurassic sedimentary rocks cropping out in the moghan area. studied sequence consists of carbonates bounded at both base and top by clastic deposits. studied carbonate deposits provide an assemblage of benthic foraminifera as well as calcareous algae. the stratigraphi...

It is proved that lim inf n→∞ (pn+1 − pn) < 7× 10, where pn is the n-th prime. Our method is a refinement of the recent work of Goldston, Pintz and Yildirim on the small gaps between consecutive primes. A major ingredient of the proof is a stronger version of the Bombieri-Vinogradov theorem that is applicable when the moduli are free from large prime divisors only (see Theorem 2 below), but it ...

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