The aim of this study was to prepare orally disintegrating tablets (ODTs) containingdexamethasone (DEX) by direct compression method with sufficient hardness and rapiddisintegration time. In order to save time, money, and human resources in designing andimprovement of formulation, the statistical software Design Expert is used. Box–Behnkenresponse surface methodology was applied to evaluate and...

Curcumin is an herbal plant with great therapeutic applications. Although it is useful in treating several diseases, its low solubility in water and low bioavailability in living systems are limiting factors in using curcumin as a medicine. One way to overcome these shortcomings is the production of curcumin micro/nano particles. In this research, the particles of curcumin loaded with polycapro...

Cauliflower-like nanostructure of cadmium oxide was synthesized by utilizing mechanochemical reaction followed calcination procedure for the first time. The design of experiment (DOE) by Taguchi method was used to study influence of the chosen factors and to consider optimum conditions of the experiments. The temperature of calcining, the duration of milling, the duration of calcining and react...

Automotive emission is becoming a critical threat to today’s human health. Many researchers are studying engine designs leading to less fuel consumption. Gearbox selection plays a key role in an engine design. In this study, Taguchi quality engineering method is employed, and optimum gear ratios in a five speed gear box is obtained. A table of various gear ratios is suggested by design o...

  Friction-stir welding process is a novel method of solid state welding, which produces heat due to friction between the pin, the shoulder and the workpiece. This heat causes a paste area. Shoulder pressure and pin spin cause edges integration and lead to welding. In this study, firstly, the feasibility of welding of steel sheet (EN10130) with a thickness of 1.5mm has been tested by 58 experim...

The oil content of the wax produced in a dewaxing process is the key economic parameter that should be reduced as much as possible. Some factors such as the type of solvents, cooling rate, temperature, and solvent to oil ratio influence the dewaxing process. Due to the fact that crude oil differs from place to place and since the operational conditions for wax extraction vary for different type...

Honing is a process for finishing surfaces to obtain smooth surface. This process is used for final polish of inner parts such as engines cylinders. Optimizing this process has always been a big challenge for mass production of cylinder blocks of internal combustion engines. Honing process has some variable parameters, thus to get their optimum rates the automobile cylinders were tested. In thi...