نتایج جستجو برای: docking distribution networks
تعداد نتایج: 1027219 فیلتر نتایج به سال:
Introduction: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor derivatives play an important role in the treatment of cancer. We aim to construct 2D-QSAR models using various chemometrics using 4-anilinoquinazoline-containing EGFR TKIs. In addition, the binding profile of these compounds was evaluated using a docking study. Materials and Methods: In this study, 122 compounds of...
Self-healing group key distribution is a primitive aimed to achieve robust key distribution in wireless sensor networks (WSNs) over lossy communication channels. However, all the existing self-healing group key distribution schemes in the literature are designed for homogenous WSNs that do not scale. In contract, heterogeneous WSNs have better scalability and performance. We are thus motivated ...
Despite the unconditionally secure theory of the Quantum Key Distribution (QKD), several attacks have been successfully implemented against commercial QKD systems. Those systems have exhibited some flaws, as the secret key rate of corresponding protocols remains unaltered, while the eavesdropper obtains the entire secret key. We propose the negative acknowledgment state quantum key distribution...
Heat Shock Protein 90 was a key molecular chaperone involved in the proteome stability maintenance and its interference in many signaling networks associated with cancer progression, makes it of an important target for cancer therapeutics. The present study aimed to identify potential lead molecule among the selected heterocyclic compounds against Human Hsp90 (PDB: 1YET) through docking using G...
To achieve high biological specificity, protein kinases and phosphatases often recognize their targets through interactions that occur outside of the active site. Although the role of modular protein-protein interaction domains in kinase and phosphatase signaling has been well characterized, it is becoming clear that many kinases and phosphatases utilize docking interactions - recognition of a ...
This study addresses the pickup and delivery problem for cross-docking strategy, in which shipments are allowed to be transferred from suppliers to retailers directly as well as through cross-docks. Usual models that investigate vehicle routing in cross-docking networks force all vehicles to stop at the cross-dock even if a shipment is about to a full truckload or the vehicle collects and deliv...
Smart grid enhances optimization in generation, distribution and consumption of the electricity by integrating information and communication technologies into the grid. Today, utilities are moving towards smart grid applications, most common one being deployment of smart meters in advanced metering infrastructure, and the first technical challenge they face is the huge volume of data generated ...
Background: Providing safe drinking water has critical importance to human societies. The aim of this study was to investigate microbiological quality of drinking water in distribution system of urban and rural regions of Ijroud, in Zanjan province. Materials and Methods: In present descriptive study, the microbiological examination of drinking water was conducted in 15 facilities with...
The main functional purpose of a water distribution network is to transport water from a source to several domestic and industrial units while at the same time satisfying various requirements on hydraulic response. All the water distribution networks perform two basic operations: firstly the water network needs to deliver adequate amounts of water to meet specific requirements, and secondly the...
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