Introduction: Regulators of G-protein signaling protein negatively control G protein -coupled receptor signaling duration by accelerating Gα subunit guanosine triphosphate hydrolysis. Since regulator of G-protein signaling4 has an important role in modulating morphine effects at the cellular level and the exact mechanism(s) of adrenalectomy-induced morphine sensitization have not been fully cl...

Here, we developed a rapid and quantitative one-step severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigen assay based on protein-induced fluorescence enhancement (PIFE) of nucleocapsid (N) protein DNA aptamer.

phosphoenolpyruvate carboxykinase (pepck) has been shown to be present in plants and animals, playing different metabolic roles in different tissues. the basic role of this enzyme is its contribution in the gluconeogenesis pathway. evidences have shown that pepck may play a role in metabolism of nitrogenous compounds in developing seeds of legumes. in this research, pepck gene expression and th...

Understanding protein interactions within the complexity of a living cell is challenging, but techniques coupling affinity purification and mass spectrometry have enabled important progress to be made in the past 15 years. As identification of protein-protein interactions is becoming easier, the quantification of the interaction dynamics is the next frontier. Several quantitative mass spectrome...