نتایج جستجو برای: autoclaved leishmania major alm
تعداد نتایج: 630960 فیلتر نتایج به سال:
In the current study, we evaluated the mechanism of action of miltefosine, which is the first effective and safe oral treatment for visceral leishmaniasis, in Leishmania amazonensis promastigotes. Miltefosine induced a process of programmed cell death, which was determined by the externalization of phosphatidylserine, the incorporation of propidium iodide, cell-cycle arrest at the sub-G0/G1 pha...
Leishmania spp. are intracellular protozoan parasites that cause a wide spectrum of diseases in humans and dogs worldwide. However, monitoring of the Leishmania burden in its different hosts is still based on cumbersome and poorly sensitive methods. Here we have developed a highly accurate real-time PCR assay with which to reproducibly detect and quantify the relative Leishmania major burden in...
Current therapy for leishmaniasis is not satisfactory. We describe the in vitro antiproliferative effects of new thiadiazine derivatives against Leishmania amazonensis. The compounds were found to be active against the amastigote form of the parasite, inhibiting parasite growing, from 10 to 89%, at a concentration of 100 ng/ml. This activity suggests that thiadiazine derivatives could be consid...
Background and purpose: Leishmaniasis is an important tropical disease in Iran and the world. Despite extensive effort to make a vaccine, no success was achieved. Moreover, routine methods have failed to control and cut the spread of this disease. Hence, the major aim of this study was to identify and determine the Leishmania infections in the vector and the ecological and biological criteria o...
Transcriptome Analysis May Be Beneficial for Identification of Specific Pathways in Host Cell-Leishmania major Interactions(letter to editor)
A.1.) Leishmania major sphingolipids and ethanolamine lipids ......................................... 3 A.1.a.) Sphingolipids are essential for differentiation but not growth in Leishmania .................... 3 A.1.b.) Leishmania salvage and remodelling of host sphingolipids in amastigote survival and acidocalcisome biogenesis. ....................................................................
this experiment was conducted to evaluate the effect of increasing levels of alfalfa leaf meal (alm) on egg production, egg traits and blood parameters of laying hens with 144 hy-line (w36) laying hens from 65-75 weeks of age in 4 treatments, 3 replicates and 12 hens in each replicate in a completely randomized design. experimental groups included: 1) control group, 2) group with 1% of alm, 3) ...
Introduction: Cutaneous Leishmaniasis (CL) is a parasitic disease caused by Leishmania species. Currently accessible treatments remain insufficient, and there is pressure to develop suitable and effectual options. In this study, we used different concentrations of podophyllin in vitro on leishmania parasites and then on leishmaniasis lesions in mice and compared their efficacy. Method: We used ...
INTRODUCTION The combination of Adenosine (A), lidocaine (L) and Mg(2+) (M) (ALM) has demonstrated cardioprotective and resuscitative properties in models of cardiac arrest and hemorrhagic shock. This study evaluates whether ALM also demonstrates organ protective properties in an endotoxemic porcine model. METHODS Pigs (37 to 42 kg) were randomized into: 1) Control (n = 8) or 2) ALM (n = 8) f...
Since pension funds are among the most important and effective organizations in economic and social environments, it is critical to study their problems ahead. Asset and liability management (ALM) is a useful tool to study pension funds and their stakeholders. This paper tries to understand the key factors effecting on ALM and to analyze them using system dynamics. Fuzzy inference engine is als...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید