The effects of cis-diamminedichloroplatinum (NSC I 19875)on murine and human hemopoietic precursor cells were studied in culture. When murine cells from normal and actively regenerating marrows were exposed to cis diamminedichloroplatinum in culture, washed free of the agent, and assayed for the surviving hemopoietic precursor cells, similar sensitivity curves were obtained. This result indicat...

Using Greedy Clustering Method to Solve Capacitated Location-Routing Problem with Fuzzy Demands Abstract In this paper, the capacitated location routing problem with fuzzy demands (CLRP_FD) is considered. In CLRP_FD, facility location problem (FLP) and vehicle routing problem (VRP) are observed simultaneously. Indeed the vehicles and the depots have a predefined capacity to serve the customerst...

The nongenomic action of progesterone (P) on capacitated sperm in mediating acrosomal exocytosis operates through transmembrane signal transduction involving increased intracellular calcium ions and modulation of protein kinases and phospholipid metabolism through a second messenger pathway. Conflicting views exist regarding the nature of the nongenomic receptor of P. It is thought to be a cell...

Hub colonization and subsequent intraluminal progression due to frequent opening and manipulation of intravenous systems is the cause of many catheter-related infections (CRI). A prospective, comparative, randomized study was performed to assess a new closed-needleless hub device (CLAVE) compared with conventional open systems (COS). End-points were hub and skin colonization, catheter tip colon...

The effects of cis-diamminedichloroplatinum (NSC I 19875)on murine and human hemopoietic precursor cells were studied in culture. When murine cells from normal and actively regenerating marrows were exposed to cis diamminedichloroplatinum in culture, washed free of the agent, and assayed for the surviving hemopoietic precursor cells, similar sensitivity curves were obtained. This result indicat...

hub location problems are among the extensions ofclassical location problems that have numerous applications in designingtransportation, postal, and telecommunication networks. despite the evidentattention of researchers to these problems, there are few studies on designinghub networks under uncertainty and disruption. in this study, the capacitatedsingle allocation hub location problem under d...

Web Services (WS) have emerged as an industry standard attracting the attention of the scientific community as technological alternative for implementing computational portals. Using the OpenCF computational framework, we develop the p-hub Web Service Portal (p-HubWSP) to provide a platform with capabilities for the efficient execution of metaheuristics for p-hub problems through the Internet. ...