purpose: to compare the efficacy and safety of xalatan(r) with generic latanoprost (xalabiost) in glaucoma. methods: in this randomized crossover study, 17 patients with primary open angle glaucoma or ocular hypertension were randomized into 2 groups. group a received xalatan for 6 weeks followed by xalabiost for 10 weeks. group b received xalabiost for 6 weeks which was then crossed over to xa...

Purpose: To explore community pharmacists’ perception of the sale of non-clinically proven health supplements and over-the-counter (OTC) products available in Penang, Malaysia. Methods: A cross-sectional survey using a self-completed postal questionnaire was conducted in July 2010 among 200 community pharmacists practicing in Penang Island. Results: Fifty six pharmacists participated in the stu...

lf as the grammatical locus of semantic interpretation in minimalism implies that lf is the only level at which any structural condition can be checked. accordingly, cross over effects provides some evidence for the existence of lf. to provide further evidence for the universality of cross over effects at lf, a comparative research between persian-english, turkish-english and persian-turkish ha...

Crossover clinical trials can provide substantial benefits by eliminating inter-patient variation from treatment comparisons and by allowing multiple observations of each patient. They are particularly useful when sample sizes are necessarily small. These advantages proved particularly valuable in an assessment of clot prevention in children undergoing haemodialysis. Only small numbers of child...

In common with most forms of designed experiment, crossover trials can be affected by missing data. Attempts to devise designs that can mitigate the possible effects of missing data, such as loss of efficiency, or even inestimability of certain contrasts, have been proposed. However, a potentially serious effect of missing data that has not been addressed in designs hitherto is that the treatme...