normal 0 false false false en-us x-none fa background : circulating endothelial cells (cecs) and e-selectin are known as sensitive and specific markers of endothelial dysfunction. this study investigated whether cecs and e-selectin are surrogate biomarkers of preeclampsia and if measurement of cecs and e-selectin, early in the third trimester, could be a means of predicting preeclampsia. method...

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by loss of tolerance toward self-nucleic acids, autoantibody production, interferon expression and signaling, defect in the regulatory T (T reg ) cell compartment. In this work, we identified that platelets from patients with active SLE preferentially interacted cells via P-selectin/P-selectin glycoprotein ligand-...

Introduction: Psoriasis is an inflammatory skin disease in which abnormal individual immune reactivity plays an important role. Eselectin and P-selectin are adhesion molecules expressed on vascular endothelial cells in several inflammatory skin diseases, including psoriasis. The aim of the present study was to describe selected immunological changes, concerning adhesion molecules status (sEsele...

background: in the visceral leishmaniasis (vl), parasites reside in reticuluendothelial system, mainly in macrophages. endothelial selectin (e-selectin) might play an important role in leukocyte-endothelium interactions and inflammatory cell recruitment. the aim of this study was determining e-selectin level and its polymorphism in three groups, patients, seroposi­tive and healthy individuals. ...

Abstract Introduction There remains a paucity of novel therapeutics for limb salvage in patients with critical ischemia (CLI) whom revascularization procedures have failed and amputation is imminent. We shown that E-selectin+/Mesenchymal Stem Cell (MSC) injections into the ischemic tissue CLI mouse model improves function. Thus, we sought to determine mechanism action E-selectin+/MSC’s pro-angi...

Elevated levels of several endothelial markers, including CD31, VEGFR-2, ICAM-1, VCAM-1, E-selectin, P-selectin and vWF, in lung tissue circulation support an important role the pulmonary endothelium local systemic COVID-19 pathologyhttps://bit.ly/3eQObIR

the e-selectin mediates the interaction of activated endothelial cells with leukocytes and plays a fundamental role in the pathogenesis of asthma. it has been suggested that an s/r (serine128arginine) polymorphism of e-selectin alters ligand binding function. our purpose in this study was to determine whether this serine128arginine polymorphism influences the risk of asthma and also to analyze ...

Abstract Background Myeloid cells express microparticles that could increase the expression of adhesion molecules including P-selectin. We aimed to evaluate level soluble P-selectin (sP-selectin) and prothrombin fragment 1 + 2 (F1 2), determine correlation sP-selectin with leukocyte count F1 levels in acute myeloid leukemia (AML) chronic (CML) patients. Methods Patients newly diagnosed AML ( n ...