hydrogels, due to their unique potentials such as high-water content and hydrophilicity are interest for the controlled release of drug molecules. the present study aims to create a controlled-release system through the preparation and characterization of hydrogels based on ph-sensitive polymers such as poly (acrylic acid). poly (acrylic acid), p(aa), hydrogel has been synthesized by radical po...

A novel pH-responsive superabsorbent hydrogel based on gelatin was prepared through crosslinking copolymerization of poly (acrylic acid) and poly (itaconic acid). The copolymerization conditions including monomers, initiator, gelatin and crosslinker concentration, reaction temperature, and neutralization percent were systematically optimized to achieve a hydrogel with swelling capacity as high ...

today hydrogels are considered as the materials that are able to play important role in drug delivery systems. to design an effective hydrogel applicable network, mathematical modeling has a critical role. a successful drug delivery device relies not only on intelligent network design but also on accurate prior mathematical modeling of drug release profiles. in this study, the modeling of the i...

The deformation behavior of a pH-sensitive hydrogel micro-fluidic valve system is investigated using inhomogeneous gel deformation theory, in which the fluid-structure interaction (FSI) of the gel solid and fluid flow in the pipe is considered. We use a finite element method with a well adopted hydrogel constitutive equation, which is coded in commercial software, ABAQUS, to simulate the hydrog...

in the present work a ph-dependent cloud point extraction procedure using ph-sensitive hydrogel polymer was applied for preconcentration and spectrophotometric determination of the hg(ii) as its thio micher's ketone complex. central composite design (ccd) and response surface method were applied to design the experiments and find out the optimum conditions. four factors entitled concentration o...

This computational study investigates the sensing and actuating behavior of a pH-sensitive hydrogel-based microfluidic flow controller. This hydrogel-based flow controller has inherent advantage in its unique stimuli-sensitive properties, removing the need for an external power supply. The predicted swelling behavior the hydrogel is validated with steady-state and transient experiments. We then...

a key parameter for the application of polymer gels in water shut off treatment is the adsorption of polymer gel onto the rock surface. so, the adsorption properties of a nanocomposite hydrogel were discussed in this research by crosslinking of sulfonated polyacrylamide/sodium montmorillonite aqueous solutions with chromium triacetate. the x-ray diffraction patterns indicated that exfoliated ty...

A key parameter for the application of polymer gels in water shut off treatment is the adsorption of polymer gel onto the rock surface. So, the adsorption properties of a nanocomposite hydrogel were discussed in this research by crosslinking of sulfonated polyacrylamide/sodium montmorillonite aqueous solutions with chromium triacetate. The X-ray diffraction patterns indicated that exfoliated ty...

Hydrogels, due to their unique potentials such as high-water content and hydrophilicity are interest for the controlled release of drug molecules. The present study aims to create a controlled-release system through the preparation and characterization of hydrogels based on pH-sensitive polymers such as poly (acrylic acid). Poly (acrylic acid), p(AA), hydrogel has been synthesized by radical po...