We propose a Generic Dialogue Architecture (GDA) to implement and research natural language dialogue systems to access information locally or over the web. The GDA is based on the concepts of messages and managers and has been designed “top-down” to be flexible enough to implement and research any theoretical background in dialogue research.

EDA tools have facilitated the design of ever more complex integrated circuits each year. Synthetic biology would also benefit from the development of genetic design automation (GDA) tools. Existing GDA tools require biologists to design genetic circuits at the molecular level, roughly equivalent to designing electronic circuits at the layout level. Analysis of these circuits is also performed ...

BACKGROUND The progesterone-regulated glycoprotein glycodelin-A (GdA), secreted by the decidualized endometrium at high concentrations in primates, inhibits the maternal immune response against fetal antigens and thereby contributes to the tolerance of the semi-allogenic fetus during a normal pregnancy. Our earlier studies demonstrated the ability of GdA to induce an intrinsic apoptotic cascade...

OBJECTIVE Gestational diabetes mellitus (GDM) is a common metabolic disorder of pregnancy. Patients with GDM are at risk for high fetal mortality and gestational complications associated with reduced immune tolerance and abnormal carbohydrate metabolism. Glycodelin-A (GdA) is an abundant decidual glycoprotein with glycosylation-dependent immunomodulatory activities. We hypothesized that aberran...

Although several recent studies have been published on goal reasoning (i.e., the study of agents that can self-select their goals), none have focused on the task of learning and acting on large state and action spaces. We introduce GDA-C, a case-based goal reasoning algorithm that divides the state and action space among cooperating learning agents. Cooperation between agents emerges because (1...