background: the association between interleukin‑6 (il‑6) (‑174g/c) gene polymorphisms and level of tissue breakdown and periodontal disease progression is unknown. the present study investigated quantitative parameters of interdental papilla in chronic periodontitis (cp) patients with il‑6 (‑174g/c) gene polymorphisms. materials and methods: sixty gingival samples were studied. after determinat...

Background: Chemerin is and adipokine produced and secreted by adipose tissue and is associated with functions such as insulin resistance, inflammation, and blood pressure regulation. The purpose of the present study was the determination of serum chemerin level in an Iranian population with metabolic syndrome and its comparison with healthy individuals. Materials and Methods: The study subj...

Objective: Crocinisa saffron constituent with a potent anti-oxidant activity. The present study investigated the effects of crocin and insulin treatments (alone or in combination) on cardiac function and pathology in diabetic rats. Materials and Methods: Diabetes was induced by intraperitoneal (i.p.) injection of streptozotocin (STZ, 50 mg/kg). Thereafter, crocin (5, 10 and 20 mg/kg, i.p.), sub...

background: it is well known that the development of brain oxidative stress is one of the most serious complications of arterial hypertension that evokes brain tissue damage. the aim of this study was to examine the effects of atorvastatin treatment (20 mg/kg/day), as an antioxidant, to prevent the brain tissue oxidative stress in the hypertensive (htn) rats. methods: experiments were performed...

background: the appendix is considered as part of the gut-associated lymphoid tissue; however, lymphocyte subsets in this tissue are not fully defined. objective: to investigate and compare the function and phenotype of lymphocyte subsets in peripheral blood and appendix of patients with normal and inflamed appendix tissues. methods: peripheral blood samples and appendiceal mononuclear cells we...

objective(s): visfatin and vaspin are secreted by adipose tissue and play key roles in glucose homeostasis and subsequently are potential targets for diabetes treatment. resveratrol (rvs) corrects insulin secretion and improves insulin sensitivity. we investigated the rvs effects on serum antioxidants, insulin and glucose levels, also visfatin and vaspin genes expression in adipose tissue of st...

Objective(s): Visfatin and vaspin are secreted by adipose tissue and play key roles in glucose homeostasis and subsequently are potential targets for diabetes treatment. Resveratrol (RVS) corrects insulin secretion and improves insulin sensitivity. We investigated the RVS effects on serum antioxidants, insulin and glucose levels, also visfatin and vaspin genes expression in adipose tissue of st...

simultaneous exposure of highly-used chemical and physical agents are expected to happen in many occupations. in the present study the impact of simultaneous exposure to noise and formaldehyde on oxidative stress in blood and liver tissue of rat was investigated. animal study was conducted in the school of public health, shahid beheshti university of medical scineces, tehran, iran in 2013. a to...