Abstract Background Endometrial carcinoma is a frequently diagnosed cancer among females. LncRNAs are reported to be associated with various cancers. Their biological roles in endometrial progression an emerging scientific area. LINC00665 can exert significant role many However, its potential function still poorly known. Method qRT-PCR was carried out test expression of and HMGA1. Western blot ...

MiR-520d-3p has recently been reported to have anti-tumor function in several cancers, including glioma and gastric cancer. However, the biological its mechanism of action remain unclear cervical cancer (CC). In this study, we observed that miR-520d-3p expression was lowly expressed CC specimens compared with adjacent normal using reverse transcription quantitative PCR. Moreover, low correlated...

background and objectives: numerous procedures in biology and medicine require the counting of cells. direct enumer- ation of colony forming units (cfus) is time-consuming and dreary accurate cell counting on plates with high numbers of cfus is error prone. in this study we report a new indirect cell counting method that was developed based on the use of redsafe fluorometric assay. the usefulne...

Objective(s): The Janus kinase-signal transducers and activators of transcription signaling pathway (JAK/STAT pathway) play an important role in proliferation of breast cancer cells. Previous data showed that inhibition of STAT3 suppresses the growth of breast cancer cells, but the associated mechanisms are not well understood. This study aims to investigate the effect and associated mechanisms...

Background & Aim:Extracts of Roselle calyx,   possess compounds which could be considered as a great source of natural antioxidants.   In this project, antioxidant activities, phenolic compounds content and their   correlation analysis on calices of Roselle (Hibiscus sabdariffa) was investigated.  Experimental: Total polyphenolic compound, flavonoids and anthoc...

Many people suffer from hair loss and abnormal skin pigmentation, highlighting the need for simple assays to support drug discovery research. Current have various limitations, such as being in vitro only, not sensitive enough, or unquantifiable. We took advantage of bilateral symmetry large size mouse whisker follicles develop a novel vivo assay called “whisker follicle microinjection assay”. I...

background: transient and stable transformation of host plants are the common techniques to produce transgenic plants. however, the main drawback of stable transformation is the fact that it takes quite a long time to produce a transgenic line. while, transient gene expression is a quick method to produce recombinant proteins in plants.  objective: the main goal of the present study was to eval...