Abstract Background The purpose of this study was to develop protein-/peptide-loaded nanoparticle-based delivery system, which can efficiently deliver therapeutic molecules the lung via pulmonary delivery. chitosan nanoparticles were prepared by ionic gelation method, and bovine serum albumin used as a model protein. These characterized for size, zeta potential, encapsulation efficiency, cell c...

Protein nanoparticles are potentially valuable carriers for drug delivery, because they can be easily designed to perform various functions such as targeting specific cells and penetration of tissues.

  Background and Objectives: Preterm labor is a serious problem in obstetrics, accounting for 70% of perinatal mortality. High sensitive C - reactive protein (HS-CRP) is a sensitive marker of Inflammation. Our aim in this study was to determine Amniotic fluid hs-CRP concentration and its correlation with pre-Term delivery.   Materials and methods: This prospective study was conducted on 90 p...

objective(s): p-glycoprotein (p-gp) is an efflux protein, the overexpression of which has been associated with multidrug resistance in various cancers. although sirna delivery to reverse p-gp expression may be promising for sensitizing of tumor cells to cytotoxic drugs, the therapeutic use of sirna requires effective carriers that can deliver sirna intracellularly with minimal toxicity on targe...