Haematopoietic growth factors constitute an important group of proteins that predominantly regulate the process of haematopoiesis. While some of these proteins have a very broad array of action on very early haematopoietic progenitors leading to multi-lineage increases in haematopoietic cell production and differentiation, others act in a restricted manner on specific committed terminally diffe...

One of the most frequent precipitating factors for attacks of porphyria is the administration of drugs. Use of drugs with porphyrinogenic potential often worsens the condition and often poses a therapeutic dilemma. A 23-year-old female patient presented to the casualty room with abdominal pain, chest pain and vomiting. Her past medical history was significant with episodes of generalised abdomi...

Soft contact lenses are widely used for correction of refractive errors and in diseases related to corneal surface irregularities. In this case series we have used soft contact lenses in treatment of patients having bullous keratopathy, corneal ulcer, dry eye, trichiasis and corneal perforation. Soft contact lenses were found to be superior than conventional method of treatment and they have re...

Research on human enteroviruses has resulted in the identification of more than 100 enterovirus types, which use more than 10 protein receptors and/or attachment factors required in cell binding and initiation of the replication cycle. Many of these "viral" receptors are overexpressed in cancer cells. Receptor binding and the ability to replicate in specific target cells define the tropism and ...

Background: Phenazopyridine is often prescribed for patients suffering from urinary tract infections as its local analgesic properties can provide immediate symptomatic improvement. It is classically taken for two days while awaiting antibiotic effect. It is available without a prescription in the United States under the trade names: Azo Urinary Pain Relief, Uricalm, and Uristat. Common adverse...

Correspondence: Joseph G Verbalis Professor of Medicine and Endocrinology, and Chief, Endocrinology and Metabolism, Division of Endocrinology and Metabolism, Georgetown University Medical Center, Building D, Suite 232, 4000 reservoir road Nw, washington, DC 20007, USA Email [email protected] Introduction: The available treatment options for euvolemic and hypervolemic hyponatremia are limi...

Modem dermatology looks more and more closely in to "old" substances wich proved to be effecti ve and safe. In addition, most of them are much cheaper than the new compounds. Urea is one of the o ld substances which were used more and more often in topica( therapy of dermatoses, either alone or in combination wi th a steroid, anthralin, retinoic acid or salicylic acid. In this paper, biochemist...