enhanced immune cell trafficking into the central nervous system (cns) and disruption of the blood brain barrier are pathophysiological hallmarks of neuroinflammatory disorders like multiple sclerosis (ms) and its animal model, experimental autoimmune encephalomyelitis (eae). however, recent studies suggest that the coagulation and the contact-kinin system might also be involved in ms developme...

basic research on the autoimmune disease multiple sclerosis has been performed mainly on its animal model namely experimental allergic encephalomyelitis. there are many different approaches established to get this model. despite the existence of many references in literature in this regard, we have been faced with many difficulties generating the model suitable for studying different therapies....

Vegetarianism is an old classic eating behavior that leads to lessening of several health risk factors. Vegetarian diet is reported to improve control of blood glucose concentration, to lower insulin requirement and to aid in weight control in diabetic patients. However, there is no evidence for the prevalence of diabetes mellitus to be significantly lower in vegetarians than in non-vegetarians...

the most popular animal models of alzheimer’s disease (ad) are transgenic mice expressing human genes with known mutations which do not represent the most abundant sporadic form of the disease. an increasing number of genetic, vascular and psychosocial data strongly support that the octodon degus, a moderate-sized and diurnal precocial rodent, provides a naturalistic model for the study of the ...

How much does language influence how we think? How far are the categories of our language contingent and culture-specific? Few questions are of greater significance to the social sciences. In this paper we attempt to demonstrate that linguistic semantics can address these questions with rigour and precision, by analysing some examples of cultural 'key words' in several languages. We want to arg...

This study explored touchscreen keyboards using high precision touchscreen strategies. Phase one evaluated three possible monitor positions: 30, 45, and 75 degrees from horizontal. Results indicate that the 75 degree angle, approximately the standard monitor position, resulted in more fatigue and lower preference ratings. Phase two collected touch bias and key size data for the 30 degree angle....