In the present study, the genotoxicity of acrylamide (AA) was investigated in HepG2 cells using SCGE. Additionally, the influence of ethanol on the modulation of AA-induced DNA-migration caused by CYP2E1-upregulation and/or GSH-depletion was examined in the same cell line. For the ethanol/AA combination assays, the cells were treated with ethanol for 24h prior to exposure to 5mM AA for another ...

The report by the National Research Council of the US National Academy of Sciences, Toxicity Testing in the 21st Century: A Vision and a Strategy, has prompted a discussion about renewing regulatory toxicology - especially for chemicals - by harnessing in vitro tests, in silico approaches, and testing in lower organisms. The key change is basing the assessments on mechanisms and toxicant modes ...

In order to study the effect of foliar applications of micronutrients on yield, extraction oil production and chemical composition of pot marigold (Calendula officinalis), two experiments were conducted in the randomized complete block design with three replications in Shahrekord, Iran during two growing seasons 2014 and 2015. The objectives of this study were to determine the effects of foliar...

Rice-rapeseed relay cropping is an effective way to use winter fallow fields and increaseland use efficiency. However, the overlapping period of 10–15 days for rice-rapeseedcultivation results in reduced winter survival and less yields. Therefore, in this study, weinvestigated if the treatment of oil rape seeds with paclobutrazol (PAC) improves its winterhardiness and yields by altering its cro...

The aim of the current study was to describe the role and mechanism of Bacillus amyloliquefaciens Y1 against the root-knot nematode, Meloidogyne incognita, under in vitro and in vivo conditions. Initially, the exposure of the bacterial culture supernatant and crude extract of Y1 to M. incognita significantly inhibited the hatching of eggs and caused the mortality of second-stage juveniles (J2),...

to investigate the effects of priming and foliar spray by 24-epibrassinolide (ebr) on some of marigold morphological, biological and biochemical traits, an experiment was conducted as factorial on completely randomized design with three replications at experimental laboratory of department of horticulture, shahid bahonar university of kerman in 2014. each of priming and foliar spray of ebr had ...

The effects of different concentrations of copper (0–800 μmol) on growth, protein contents, peroxidase (POD), catalase (CAT), superoxide dismutase (SOD), and phenylalanine ammonia-lyase (PAL) in Jatropha curcas L. seedlings were assessed by means of pot experiments. Results suggested that increased copper concentrations lead to decreased shoot elongation and seedling biomass. Protein content in...

abstract recently weed scientist are more interested in weed management by allelopathy . the main objective of the study was to evaluate allelopathic potential of sunflower on redroot pigweed and common lambsquarter. this study was conducted in two series of laboratory and greenhouse experiments. under laboratory conditions, leaf, stem and root aqueous extracts of sunflower at 0%, 2.5%, 5%, 7.5...