BACKGROUND Adhesins of pathogens recognise the glycans on the host cell and mediate adherence. They are also crucial for determining the tissue preferences of pathogens. Currently, glyco-nanomaterials provide potential tool for antimicrobial therapy. We demonstrate that properly glyco-tailored inclusion bodies can specifically bind pathogen adhesins and release therapeutic substances. RESULTS...

MJM: Please describe how your divide you practice on a week-to-week basis. Dr. Saba: I work about one week a month doing hospitalization at the Lachine Hospital in Montreal. I do another week of mixed hospitalization, either with intensive care or without intensive care. I do about two weeks a month altogether in practice at my clinic; I try to be in my office at least three weeks out of four, ...

Background: Asthma is a chronic inflammatory disease, therefore inhaled corticosteroid (ICS) should be as the cornerstone of asthma treatment. However patients tend to rely on short-acting β2-agonist (SABA) due immediate symptom relief and underuse ICS, thereby undertreating underlying inflammation. As part multi-country SABA use IN (SABINA) III study, we aimed describe prescription patterns as...

In banana, drought responsive gene expression profiles of drought-tolerant and sensitive genotypes remain largely unexplored. In this research, the transcriptome of drought-tolerant banana cultivar (Saba, ABB genome) and sensitive cultivar (Grand Naine, AAA genome) was monitored using mRNA-Seq under control and drought stress condition. A total of 162.36 million reads from tolerant and 126.58 m...

OBJECTIVE To compare asthma-related health care resource utilization among a matched cohort of asthma patients using inhaled corticosteroids (ICSs) plus either montelukast (MON) or salmeterol (SAL) as combination therapy for asthma, during a time prior to the availability of fixed-dose combinations of ICS/SAL. METHODS A retrospective analysis using the PHARMetrics patient-centric claims datab...