Introduction: Memantine as N-Methyl-D-aspartic acid (NMDA) receptor antagonist is used in some neurological disorders. It has been reported that memantine has modulatory effects on the somatosensory information processing in healthy subjects. This study investigated the effect of memantine on electrophysiological properties of barrel cortex neurons in male rats. Methods: Single unit recording ...

During the first postnatal week, the distribution of callosal projection neurons in the rat somatosensory cortex changes from a uniform to a discontinuous pattern. To determine if this change is influenced by afferent inputs to the somatosensory cortex, the effect of both early unilateral infraorbital nerve section and unilateral removal of the dorsal thalamus on the distribution of callosal pr...

there are some conflicts about constancy of conduction velocity (cv) in a given tract of nervous system. by recording excitatory postsynaptic currents (epsc) in layer iv of the somatosensory cortex we tried to clear changes in cv of thalamocortical tract of mice aged 3 to 50 days old. field potentials and epsc were recorded in the layer iv by stimulation of ventrobasal nucleus of thalamus (vb) ...

introduction: the primary somatosensory cortex has an important role in nociceptive sensory-discriminative processing. altered peripheral inputs produced by deafferentation or by long-term changes in levels of afferent stimulation can result in plasticity of cortex. capsaicin-induced depletion of c-fiber afferents results in plasticity of the somatosensory system. plasticity includes short-term...

It is new clear that the brain of headache sufferers are different from those people without headache, theimaging study showed thickening in specific area related to communication sensory processingcalled somatosensory cortex (post central region) this we examine 36 patient, 28 them haveheadache variable duration, 8 healthy patient used as control (i.e. has no headache). The result foundthat th...

Reinforcing effects of reward on action are well established, but possible effects on sensory function are less well explored. Here, using functional magnetic resonance imaging, we assessed whether reward can influence somatosensory judgments and modulate activity in human somatosensory cortex. Participants discriminated electrical somatosensory stimuli on an index finger with correct performan...

previous studies have shown that the receptive field properties, spontaneous activity and spatio-temporal interactions of low-threshold mechanical somatosensory cells in the barrel cortex are influenced by c-fibers. in this study, we examined the effect of c-fiber depletion on response properties of barrel cortex neurons following experience dependent plasticity. methods: in this study, exterac...

Background: Pain is of stressful and unpleasant procedures after daily dressing of burn wound, so that if the burn pain is not alleviated properly, it can cause harmful effects other than discomfort. There is evidence that cathodal stimulation of somatosensory cortex can be effective in relieving acute pain. Aim: The main purpose of this study was to determine the effect of Direct Transcranial ...

Accumulating evidence demonstrates that similar neural circuits are activated during the first-hand experience of pain and the observation of pain in others. However, most functional MRI studies did not detect signal change in the primary somatosensory cortex during pain empathy. To test if the perception of pain in others involves the primary somatosensory cortex, neuromagnetic oscillatory act...