We study a firm’s cost-based sourcing decision of whether to invest in an incumbent supplier or switch to an alternative supplier in order to realise lower purchasing costs. In isolation, it can be shown that the development of an incumbent supplier (i.e., a cooperative investment) becomes more attractive, the higher the uncertainty about the price the buying firm can realise on the market and ...

Taking into account the supplier involvement in the new product development (NPD), this article focuses on the synthesis evaluation, and selection of the part design scheme in part deployment process. The concepts of performance indicator (PI) and integrated performance indicators (IPI) are introduced to measure the performance of the part design scheme and product design scheme respectively. A...

The zyxin-related LPP protein is localized at focal adhesions and cell-cell contacts and is involved in the regulation of smooth muscle cell migration. A known interaction partner of LPP in human is the tumor suppressor protein SCRIB. Knocking down scrib expression during zebrafish embryonic development results in defects of convergence and extension (C&E) movements, which occur during gastrula...

As supply chains continue to globalize, the need for robust supplier qualification and supplier selection and evaluation programs becomes increasingly critical. In this context, this paper aims to present a methodological approach for the optimization of the procurement processes in today’s globalized supply chains. More specifically, we first provide a categorization of the relevant past resea...

This paper presents a linear fractional programming problem (LFPP) with rough interval coefficients (RICs) in the objective function. It shows that LFPP RICs function can be converted into (LPP) by using variable transformations. To solve this problem, we will make two LPP (ICs). Next, those four LPPs constructed under these assumptions; solved classical simplex method and used MS Excel Solver....

PEA3 is a member of a subfamily of ETS domain transcription factors which is regulated by a number of signaling cascades, including the mitogen-activated protein (MAP) kinase pathways. PEA3 activates gene expression and is thought to play an important role in promoting tumor metastasis and also in neuronal development. Here, we have identified the LIM domain protein LPP as a novel coregulatory ...

In this paper, a mathematical programming model is presented for integrated problem of closed loop supply chain network design and supplier selection. The suppliers  propose discount policy based on purchase amount and loyalty of buyers which are both taken from the elements of RFM (Recency, Frequency and Monetary) technique. The main objective of this paper which is formulated by a mixed-integ...

    Supplier selection,   Multi-objective decision making,   Fuzzy Compromise programming,   Supply chain management,   Quantity discount .   Supplier selection is naturally a complex multi-objective problem including both quantitative and qualitative factors. This paper deals with this issue from a new view point. A quantity discount situation, which plays a role of motivator for buyer, is con...

Data Envelopment Analysis models are based on linear programming problems (LPP) to determine the efficiency of Decision-Making Units (DMUs). This process can be computationally intense, as a LPP has to be run for each unit. Besides, a typical DEA LPP has a large number of redundant constraints concerning the inefficient DMUs. That results in degenerate LPPs and in some cases multiple efficient ...

Due to the importance of supplier selection issue in supply chain management (SCM) and ,also,  the increasing tendency of organizations to their social responsibilities, In this paper, we survey the supplier selection issue as a multi objective problem while considering the factor of corporate social responsibility (CSR) as a mathematical parameter. The purpose of this paper is to design a mode...