The success of molecularly targeted agents (MTA) in the treatment of cancer has led to the investigation of their use in combination with other MTAs and with conventional chemotherapies. An overview of the MTAs that have emerged as Food and Drug Administration-approved drugs is presented, along with a framework for the consideration of how MTAs can best be combined to maximize therapeutic effect.

introduction: optimal child development necessitates proper nutrition in childhood. despite of improvements in child nutrition, there are still lots of challenges in proper child nutrition which shows the necessity of using the past experiences more than ever. despite of particular interest of iranians to cardinal humors (temperaments), unfortunately, families and medical staffs are not appropr...

Both DSm and minC rules of combination endeavor to process conflicts among combined beliefs better. The nature of conflicts as well as their processing during the belief combination is sketched. An presentation of the minC combination, an alternative to Dempster’s rule of combination, follows. Working domains, structures and mechanisms of the DSm and minC combination rules are compared in the b...

sometimes disagreement in regards to reading a qur’ānic verse has resulted in a paradoxical judgment and this occurs in traditions, as well. but the way in which one can consider paradoxical verses arises from the so-called ‘alājīyah traditions. the question that arises here is as follows: can the rules presented by these evidences be also extended to the paradoxical readings? if so, what are t...

When a visual target is presented with neighboring landmarks, its location can be determined both relative to the self (egocentric coding) and relative to these landmarks (allocentric coding). In the present study, we investigated (1) how allocentric coding depends on the distance between the targets and their surrounding landmarks (i.e. the spatial range) and (2) how allocentric and egocentric...

The main objective of this study is to reduce the retrieval time of a list of products by choosing the best combination of storage and retrieval rules at any time. This is why we start by implementing some storage rules in an Automated Storage/Retrieval System (Automated Storage and Retrieval System: AS/RS) fitted with a gravity conveyor while some of these rules are dedicated to storage and ot...