Flexible flow shop scheduling problem (FFS) with unrelated parallel machines contains sequencing in flow shop where, at any stage, there exists one or more processors. The objective consists of minimizing the maximum completion time. Because of NP-completeness of FFS problem, it is necessary to use heuristics method to address problems of moderate to large scale problem. Therefore, for assessme...

objective(s):berberine, a naturally occurring isoquinoline alkaloid, has shown antitumor properties in some in vitro systems. but the effect of berberine on breast cancer has not yet been completely studied. in this study, we evaluated anticancer properties of berberine in comparison to doxorubicin. materials and methods: the antiproliferative effects of berberine and doxorubicin alone and in c...

We study the dynamic assignment of cross-trained servers to stations in understaffed lines with finite buffers. Our objective is to maximize the production rate. We identify optimal server assignment policies for systems with three stations, two servers, different flexibility structures, and either deterministic service times and arbitrary buffers or exponential service times and small buffers....

label switching technology is a flexible and high performance method for forwarding layer three packets that are mapped to layer two flows. each label switch router, lsr, needs a specific label for every flow, where the number of labels depends on the mapping and granularity of flows. data and control driven methods are the most significant and popular methods in label mapping policy. the above...

Although two-phase flow is frequently encountered in various location of the process plants, there is no a general accepted and verified two-phase flow model that may be used to size lines for such conditions. An obvious example is condensate water return lines. The API method that used in this study is based on the homogeneous equilibrium flow assumption, that is, equal velocity and equal temp...

This paper proposes a Flexible Power Electronic Transformer (FPET) for the application in the micro-grids. The low frequency transformer is usually used at the Point of Common Coupling (PCC) to connect the low voltage grid and utility network to each other. The conventional 50Hz transformer results in enhanced low voltage-grid power management system during grid-connected operation. In this pap...

introduction: the tumor suppressor p53 protein can induce apoptosis in some cellular contexts. among the apoptosis-inducing genes, p53 has received the most attention for cancer gene therapy. in this study, the role of dendrosome and lipofectin mediated normal cdna of tp53 into molt-4, ccrf-cem(t-iymphoma) and k562 cell lines was assessed. material and methods: at first, ccrf-cem, mol t-4 and k...

We study the dynamic assignment of flexible servers to stations in the presence of setup costs that are incurred when servers move between stations. We focus on tandem lines with two stations and two servers with the goal of maximizing the long-run average profit. We investigate how the optimal server assignment policy for such systems depends on the magnitude of the setup costs, as well as on ...

In this paper, the problem of short-term production planning in flexible flow lines is considered. A MIP model formulation of the proportional lot sizing problem for multilevel production processes with alternatively usable machines is presented. This model is very general in terms of material routing through the system and allocation of items and machines to production stages. By definition of...