نتایج جستجو برای: foreign protein
تعداد نتایج: 1310390 فیلتر نتایج به سال:
We describe an efficient and easy procedure that allows the generation, detection and secretion of foreign proteins by the secretion apparatus of E. coli hemolysin. The gene (or gene fragment) encoding the foreign protein (or protein domain) is inserted in-frame into a residual portion of the hemolysin gene (hlyA), encoding the HlyA secretion signal (HlyAs). Generally, the expressed fusion is e...
Foreign protein Ags are incorporated into APCs and then degraded by endosomal proteases. The peptides are then mounted on MHC II molecules on the surfaces of APCs. The T cell-triggering response and, therefore, the immune response, were suggested to be governed by the degree of conformational stability of the foreign protein Ags. However, there is little evidence that a protein's conformational...
Mitochondrial antiviral signaling protein (MAVS) is an essential adaptor molecule that is responsible for antiviral signaling triggered by retinoic acid-inducible gene-I (RIG-I)-like receptors (RLRs), leading to the induction of type I interferon in innate immunity. Previous studies have shown that certain viruses evade the innate immune response by cleaving the MAVS protein. However, little is...
Lentivirus vector systems have been developed for the safe delivery of foreign genes to target tissues. However, the use of these systems for delivering specific proteins to target cells has been largely unexplored. To test this concept, the lentivirus expression plasmid pLenti was utilized to overexpress in producer cells a YFP-fusion protein that is specifically targeted to glycolipid-enriche...
با توجه به شیوع سرطان در جوامع امروزی، یافتن داروهای جدید برای درمان آن از اهمیت بالایی برخوردار است. استفاده از داروهای شیمیایی موجود به دلیل عوارض جانبی که دارند با محدودیت مصرف روبه رو می باشند. از این رو محققین درصدد یافتن مواد طبیعی با خاصیت ضد سرطانی می باشند. هدف اصلی این پایان نامه بررسی اثرات ضد سرطانی lactoferrin وwhey acidic protein موجود در شیر شتر می باشد. در تحقیق حاضر تأثیر lacto...
BACKGROUND Chimeric virus-like particles (VLP) allow the display of foreign antigens on their surface and have proved valuable in the development of safe subunit vaccines or drug delivery. However, finding an inexpensive production system and a VLP scaffold that allows stable incorporation of diverse, large foreign antigens are major challenges in this field. RESULTS In this study, a versatil...
A 52-year-old woman developed headache, throat foreign body sensation, neck pain, and fever of 3 days duration 3 months after choking on a Pearl Spot fish bone (FB). CSF contained 2,200 cells, neutrophils (90%) with normal sugar and protein. Brain MRI showed possible occipital cerebritis (figure). CT neck revealed a retropharyngeal foreign body, abscess and emphysema, and a pharyngeal fistula. ...
Diiculties in tissue transplantation result from the fact that 1-24% of host T cells are activated by proteins present on foreign tissues, and destroy them. A long-standing immunological puzzle is reconciling this phenomenon with experiments showing that only one out of 10 4 {10 6 T cells responds to a given foreign antigen (e.g., protein). Using a quantitative model, we explain how this diiere...
شوری خاک یکی از عوامل مهم محیطی است که منجر به کاهش عملکرد گیاهان زراعی می شود. شناخت مکانیسم های مقاومت گیاهان در برابر تنش ها می تواند به شناسایی ژن های مقاومت و کاربرد آن ها در اصلاح گیاهان و افزایش محدوده کشت گیاهان منجر شود. روش آنالیز expressed sequence tag (est) و داده های ریزآرایه راهی سریع و منطقی برای شناسایی ژن های نامزد جدید برای مقاومت به تنش ها می باشد. در این تحقیق تعداد 2 کتابخا...
A 69-year-old male patient visited our hospital because of a continuous low-grade fever and right back pain since 2 weeks. Enhanced computed tomography (CT) of his abdomen revealed a mass with ring enhancement (35 × 30 mm) in the Spiegel lobe as well as a needle-like foreign body. Because conservative treatment by fasting and administration of antibiotics was unsuccessful, the patient underwent...
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