Adsorption and controlled release of terbinafine hydrochloride (TER-HCl) to and from pH sensitive poly(acrylamide/maleic acid) (P(AAm/MA)) hydrogels were investigated. P(AAm/MA) hydrogels were prepared by irradiating the ternary mixtures of AAm/MA/and water by gamma-rays at ambient temperature. Antifungal drug, TER-HCl containing hydrogels, at different drug to polymer ratios, was prepared by d...

Aloe vera gel is widely used as a functional ingredient in food processing. This gel is very unstable due to its high water activity. Drying process can be used to obtain shelf stable products. Response surface methodology was used to assess the effects of solution concentration (30-60% w/w), solution temperature (30-50°C) and immersion time (4-6h) at atmospheric pressure and constant solution ...

A gel can be described as the cross-linked material that retains a large amount of solvent inside its medium and if the solvent retained is water, such material is known as hydrogel. Drug therapy of the inflammation of skin is mainly topical. This necessitates the treatment of symptoms, since in most cases causal treatment is impossible due to unknown etiology. Topical corticosteroids are the m...

Abstract: Background: Hydrotropic solid dispersion has been reported as a potential process to improve the poor solubility of drugs using conventional hydrotropes. The presented investigation described water-soluble hydrotropic system for Meloxicam (MX) sodium benzoate hydrotrope enhance and topical delivery. Thus, was prepared, characterized, converted into HSD-Meloxicam gel. prepared gel furt...

Preparation and characterization of thermoresponsive in-situ forming poloxamer hydrogel for controlled release of Nile red-loaded solid lipid nanoparticles. Nanoparticles (NPs) are cleared rapidly from systemic circulation and do not provide sustained action in most cases. To solve this problem, this investigation introduces an erodible in-situ forming gel system as potential vehicles for prolo...

Various phosphosilicate doped polypyrrole proton conductive thin films composite membranes were successfully prepared. Phosphosilicate obtained by sol-gel process mixing tetraethoxy silane with phosphoric acid at a molar ratio 1:5. The conductivity increased increasing both the content of gel and relative humidity. Temperature dependence showed Vogel-Tamman-Fulcher type behavior, indicating tha...

background: a dressing often covers the wound to accelerate its healing. hydrocolloid-type dressing to give better conditions for healing has been developed consisting of gelatin, pectin, water and hydrophilic polymer which promote healing. in recent years, much attention has been focused on the research and development of polymer hydrogels as biomaterials, such as contact lenses, wound dressin...