Objective(s): Cucurbitacins exhibit a range of anti-cancer functions. We investigated the effects of cucurbitacins D, E, and I purified from Ecballium elaterium (L.) A. Rich fruits on some apoptotic and autophagy genes in human gastric cancer cell line AGS. Materials and Methods: Using quantitative reverse transcription PCR (qRT-PCR), the expression of LC3, VEGF, BAX, caspase-3, and c-MYC genes...

Breast Cancer (BC) is considered as one of the most important causes of death worldwide. Previous studies showed that apolipoprotein B mRNA- editing catalytic polypeptide-like 3 (APOBEC3) gene deletion significantly increased the risk of BC risk in Chinese and European women. The present study aimed to assess the possible impact of APOBEC3 deletion and the risk of BC in a sample of Iranian popu...

recent l y i n a clas sroom d is sect i on we f ounu an anoma l ou s superior thyroid artery in a 60-year -ol d man . the arte ry originated f rom t he common carotid 31 mm p rox imal t o its bifurcation . rega r d i ng t o the s ex , the s i de and p lace o f o r i g i n , this could be a unique case , suggesting a need for more awarene s s o f any unpredictable anomal y whi ch may be s een i ...

let $(r,m)$ be a commutative noetherian local ring, $m$ a finitely generated $r$-module of dimension $d$, and let $i$ be an ideal of definition for $m$. in this paper, we extend cite[corollary 10(4)]{p} and also we show that if $m$ is a cohen-macaulay $r$-module and $d=2$, then $lambda(frac{widetilde{i^nm}}{jwidetilde{i^{n-1}m}})$ does not depend on $j$ for all $ngeq 1$, where $j$ is a minimal ...

Let $R$ be a commutative Noetherian ring and let $fa$, $fb$ be two ideals of $R$ such that $R/({fa+fb})$ is Artinian. Let $M$, $N$ be two finitely generated $R$-modules. We prove that $H_{fb}^j(H_{fa}^t(M,N))$ is Artinian for $j=0,1$, where $t=inf{iin{mathbb{N}_0}: H_{fa}^i(M,N)$ is not finitelygenerated $}$. Also, we prove that if $DimSupp(H_{fa}^i(M,N))leq 2$, then $H_{fb}^1(H_{fa}^i(M,N))$ i...