نتایج جستجو برای: vsvg protein
تعداد نتایج: 1234696 فیلتر نتایج به سال:
The role of dynamin and so-called accessory proteins in endocytosis is well established. However, molecular details of the function(s) of dynamin II at the Golgi are largely unclear. We demonstrate that the ubiquitously expressed syndapin II isoform interacts with the proline-rich domain (PRD) of dynamin II through its Src-homology 3 (SH3) domain. Co-immunoprecipitation of endogenous syndapin I...
For several decades, the trans-Golgi network (TGN) was considered the most distal stop and hence the ultimate protein-sorting station for distinct apical and basolateral transport carriers that reach their respective surface domains in the direct trafficking pathway. However, recent reports of apical and basolateral cargoes traversing post-Golgi compartments accessible to endocytic ligands befo...
چکیده اسیدهای چرب غیراشباع با چندین پیوند دوگانه می توانند در روندهای تولید مثلی مختلف از طریق سازوکارهای متنوعی تاثیر بگذارند. در این مطالعه تاثیرات مکمل های اسیدهای چرب امگا 3 و امگا 6 بر ویژگی های تکامل فولیکولی و استروئیدزایی تخمدان و همچنین بیان فاکتور رشد bone morphogenetic protein 15 در اووسیت، که در فولیکول زایی تخمدانی نقش دارد، بررسی شد. 30 میش 4-2 ساله-ی غیرشیرده به 3 گروه 10 تایی ت...
Ebola virus (EBOV) infects several cell types and while viral entry is known to be pH-dependent, the exact entry pathway(s) remains unknown. To gain insights into EBOV entry, the role of several inhibitors of clathrin-mediated endocytosis in blocking infection mediated by HIV pseudotyped with the EBOV envelope glycoprotein (EbGP) was examined. Wild type HIV and envelope-minus HIV pseudotyped wi...
Glutamate transporter associated protein 3-18 (GTRAP3-18) is an endoplasmic reticulum (ER)-localized protein belonging to the prenylated rab-acceptor-family interacting with small Rab GTPases, which regulate intracellular trafficking events. Its impact on secretory trafficking has not been investigated. We report here that GTRAP3-18 has an inhibitory effect on Rab1, which is involved in ER-to-G...
Sec34p/Grd20p has been implicated in endoplasmic reticulum (ER)-to-Golgi transport and/or post-Golgi trafficking events and exists in a protein complex consisting of at least eight subunits in yeast. Although the mammalian counterpart (Sec34) of Sec34p has been molecularly identified, its role and interacting partners remain undefined. In this study, we have prepared antibodies specifically aga...
In this essay, I review videos fromMolecular Biology of the Cell (MBC) depicting various aspects of plasma membrane (PM) dynamics, including the targeting of newly synthesized components and the organization of those PM invaginations called caveolae. The papers accompanying these videos describe, respectively, the constitutive export of a mutant form of the vesicular stromatitis virus coat glyc...
Viruses interact with various permissive and restrictive factors in host cells throughout their replication cycle. Cell lines that are non-permissive to viral infection have been particularly useful in discovering host cell proteins involved in viral life cycles. Here we describe the characterization of a human myeloid leukemia cell line, KG-1, that is resistant to infection by retroviruses and...
با توجه به شیوع سرطان در جوامع امروزی، یافتن داروهای جدید برای درمان آن از اهمیت بالایی برخوردار است. استفاده از داروهای شیمیایی موجود به دلیل عوارض جانبی که دارند با محدودیت مصرف روبه رو می باشند. از این رو محققین درصدد یافتن مواد طبیعی با خاصیت ضد سرطانی می باشند. هدف اصلی این پایان نامه بررسی اثرات ضد سرطانی lactoferrin وwhey acidic protein موجود در شیر شتر می باشد. در تحقیق حاضر تأثیر lacto...
With the aim of broadening the versatility of lentiviral vectors as a tool in nucleic acid research, we expanded the genetic code in the propagation of lentiviral vectors for site-specific incorporation of chemical moieties with unique properties. Through systematic exploration of the structure-function relationship of lentiviral VSVg envelope by site-specific mutagenesis and incorporation of r...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید